PHYTOCHEMICAL ANALYSIS OF ALSEODAPHNE SEMECARPIFOLIA LEAF EXTACT BY GC-MS

Authors

  • Charles A
  • Joseph M
  • Alex Ramani V

Abstract

OBJECTIVE: To explore the phytochemical constituents present in the leaves of Alseodaphne semecarpifolia using GC-MS analysis. METHODS: The shade-dried leaves of A.semecarpifolia were extracted with 80% ethanol subjected to cold percolation. The concentrated ethanolic extracts were further subjected to GC-MS. RESULTS: The alcoholic leaves extract showed 50 different types of phytoconstituents, primarily 1H-Pyrrole, 1-methyl-(33.79 %), phytol (14.66 %), coumarins (2.2%), fatty acids and its ester, terpenoids, alkaloids, phenols, and hetero cyclic containing compounds are present. CONCLUSION: A.semecarpifolia which possesses several known and unknown bioactive compounds. Most of the identified compounds by GC-MS in the leaf extracts are basically biological important. Further investigation may lead to the development of drug formulation.

Keywords: Alseodaphne semecarpifolia Nees, leaf extracts, phytochemical analysis, GC-MS. 

Downloads

Download data is not yet available.

References

Krishnaswamy NR, Chemistry of Natural Products, University Press, 1999; x.

Mukhtar MR , Zahari A, Nafiah MA, Hadi A , Thomas AH , Hiroko NF, Morita H, Litaudon M, Ahmad K. 3', 4’-Dihydrostephasubine, A New Bisbenzylisoquinoline from the Bark of Alseodaphne corneri. Heterocycles. 2009; 78:2571-2578.

Mohd Azlan Nafiah, Mat Ropi Mukhtar, Hanita Omar, Kartini Ahmad, Hiroshi Morita, Marc Litaudon, Khalijah Awang, N-Cyanomethylnorboldine: A New Aporphine Isolated from Alseodaphne perakensis (Lauraceae). Molecules, 2011; 16: 3402-3409.

Shoei-Sheng Lee, Show-Mei Chang, and Chung-Hsiung Chen, Chemical Constituents from Alseodaphne andersonii.J. Nat. Prod. 2001; 64 [12]:1548–1551.

Smolnycki WD, Moniot JL, Hidenlang DM, Miana GA., and Shamma M, Srilankine: 4- Hydroxylated Aporphine. Tetrahedron Letters, 1978; 47:4617-4620.

Parcha VM, Kaushik A,Kaushik J, Rawat MSM, and Biswas SAS, Evaluation of Antimicrobial Potential of Alseodaphne andersonii. Leaf Extracts against Pathogenic Bacteria, J. Pharmaceutical Biology.2007; 45[1]:60-63.

Parcha VM, Gahlot P and Bishwas, Antimicrobial activity of Alseodaphane keanamia extracts. Indian Perfumer. 2003; 47:87-190.

Dhillon I, Kaushik JJ, Anti-inflammatory and effect on central nervous system of Alseodaphne andersonii in experimental animal models. The pharma research, 2009; 2: 8-15.

www.dhr.gov.in/annual_report/.../basic%20medical%20sciences.pdf.

Gamble JS, Flora of Presidency of Madras.1993; 2: 1226. [re. ed]

Sasidharan, Biodiversity documentation for Kerala. Flowering Plants.2004; 6:395.

Harsha VH, Shripathi V, Hegde GR. Ethno veterinary practices in Uttara Kannada district of Karnataka. Indian .J. of Traditional Knowledge. 2005; 4[3]:253-258.

Karupusamy S, Medicinal plant used by Paliyan Tribes of Sirumalai hills of Southern India. Natural product Radiance. 2007; 6[5]:436-442.

Ayyanar M and Ignacimuthu S, Ethanomedicinal plant used by the Tribals of Triunelveli hills to treat poisonous bites and skin diseases.Indian .J. of Traditional Knowledge. 2005; 4[2]:229-236.

Yanagimoto K, Lee K.-G, Ochi H,Shibamoto T. Anti-oxidative activity of heterocyclic compounds found in coffee volatiles produced by Maillard reaction. J. Agric. Food Chem. 2002; 50:5480-5484.

Jurg Gerth, Marco Leonti, Ildiko Racz, Stefan Raduner, Jian- Zhong Chen, Xiang-Qun, Xie Karl-Heinz Altman, Meliha Karak and Andreas Zimmer. Beta-caryophyllene is a dietary cannabinoid. Proceeding of the National Academy of Sciences of the United States of America (PNAS).2008; 105[26]:9099-9104.

Hamideh Zarrinmayeh, Eric Tromiczak, Dennis M. Zimmerman , Nancy Rankl, Ken.H.Ho, Esteban Dominguez, Ana Castano, Ana Escribano, Carmen Fernandez, Alma Jimenez, William J.Hornback, Eric S.Nisenbaum et al.A novel class of positive allosteric modulators of AMPA receptors. Bioorganic &Medicinal Chemistry Letters, 2006; 16[19]: 5203-5206.

Grzegorz Gajos, Pawel Rosoff, AnettaUndas and Wieslawa Piwowarska. Effects of polysaturated Omega-3-Fatty acids on responsiveness to dual antiplatet therapy in patients undergoing percutaneous coronary intervention. Journal of the American College of Cardiology 2010; 55[16]: 1671-1678.

Bah Moustapha, Gutiérrez-Avella Dora Marina, Fuentes-Ordaz Raul, Castaneda-Moreno Raque and Martinez Mahinda.Chemical constituents of the Mexican mistletoe (Psittacanthus calyculatus) Molecules. 2011; 16: 9397-9403.

Zhou P,Takaishi Y, Duan H, Chen B,Honda G,Itoh M,Takeda Y, Kodzhimatoy OK, Lee KH. Coumarins and bicoumarin from Ferula sumbul. Anti-HIV activity and inhibition of cytokine release. Phytochemistry, 2000; 53[6]:689-97.

Shivprasad Mahadkar ,Sujata Valvi, Varsha Jadhav. Gas Chromatography Mass Spectroscopic (GC-MS) analysis of some bioactive compounds forms five medicinally relevant wild edible plants.Asian J Pharm Clin Res, 2013; 6[1]:136-139.

Dubal KN, Ghorpade PN, Kale MV. Studies on bioactive compounds of Tectaria coadunata (Wall. ex Hook. &Grev.) C.Chr. Asian J Pharm Clin Res, 2013; 6[2]:186-187.

Published

01-09-2013

How to Cite

A, C., J. M, and A. Ramani V. “PHYTOCHEMICAL ANALYSIS OF ALSEODAPHNE SEMECARPIFOLIA LEAF EXTACT BY GC-MS”. Asian Journal of Pharmaceutical and Clinical Research, vol. 6, no. 8, Sept. 2013, pp. 89-92, https://journals.innovareacademics.in/index.php/ajpcr/article/view/363.

Issue

Section

Articles