IN VITRO CYTOTOXICITY OF CARALLUMA SPECIES BY MTT AND TRYPAN BLUE DYE EXCLUSION

Authors

  • Pavan Kumar Bellamakondi Radiant Research Services Pvt Ltd, Bangalore, India
  • Ashok Godavarthi Radiant Research Services Pvt Ltd, Bangalore, India
  • Mohammed Ibrahim Nizam Institute of Pharmacy, Nalgonda, India
  • Seetaram Kulkarni Radiant Research Services Pvt Ltd, Bangalore, India
  • Ramachandra M Naik Depart of PG studies and Research in Applied Botany, Kuvempu University, Shankaraghatta, India
  • Sunitha Maradam Radiant Research Services Pvt Ltd, Bangalore, India

Abstract

Caralluma species have been reported for various traditional claims; the scientific data for possible activities have not yet been studied thoroughly. However the toxicity of a plant has to be studied for further exploration of various biological activities. Extracts were studied for their toxicity by MTT and trypan blue dye exclusion models against a panel of cancer, normal origin cell lines and EAC cells. The extracts found to be moderately toxic and showed dose dependent response.

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Author Biography

Pavan Kumar Bellamakondi, Radiant Research Services Pvt Ltd, Bangalore, India

Senior Research Associate

Research and Development

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Published

01-04-2014

How to Cite

Bellamakondi, P. K., A. Godavarthi, M. Ibrahim, S. Kulkarni, R. M. Naik, and S. Maradam. “IN VITRO CYTOTOXICITY OF CARALLUMA SPECIES BY MTT AND TRYPAN BLUE DYE EXCLUSION”. Asian Journal of Pharmaceutical and Clinical Research, vol. 7, no. 2, Apr. 2014, pp. 17-19, https://journals.innovareacademics.in/index.php/ajpcr/article/view/836.

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