REVIEW ON ENHANCEMENT OF GLUCOSE UPTAKE AND UP-REGULATION OF GLUCOSE TRANSPORTERS BY ANTIDIABETIC MEDICINAL PLANTS

  • M Gayathri
  • Gayathri Ga

Abstract

ABSTRACT
Glucose is a key fuel in mammalian cells that import by a process of facilitative diffusion mediated by glucose transporters (GLUT). A defect in GLUT
expression for prolong time leads to diabetes mellitus. Medicinal plants used in traditional treatments confirm a possibility of tackling diabetes by
regulating the GLUT activity in the body, with lesser side effects. Resistant of tissues to insulin is a major manifestation in type 2, and the cause can be
localized in defect of glucose that can be reverse by medicinal plants. In vitro, in vivo, and in silico studies of plant extracts and its active compounds
support for their multiple target mechanisms. Many medicinal plants used in the traditional medicine enhancing the translocation of GLUT and this
could lead to a new approach for treating type 2 diabetes.
Keywords: Diabetes, Glucose transporters, Mechanism of glucose transporter, Glucose transporters 4, Medicinal plants.

 

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Table 1: (Contd...)
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How to Cite
Gayathri, M., and G. Ga. “REVIEW ON ENHANCEMENT OF GLUCOSE UPTAKE AND UP-REGULATION OF GLUCOSE TRANSPORTERS BY ANTIDIABETIC MEDICINAL PLANTS”. Asian Journal of Pharmaceutical and Clinical Research, Vol. 9, no. 2, Mar. 2016, pp. 34-39, https://innovareacademics.in/journals/index.php/ajpcr/article/view/10634.
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