EVALUATION OF SERUM PROLACTIN LEVEL IN CHRONIC KIDNEY DISEASE
Objective: To study the association between chronic kidney disease (CKD) and hyperprolactinemia.
Methods: The study was conducted in 50 patients with CKD admitted in K.A.P.Viswanatham Government Medical College/M.G.M. Government
Hospital Tiruchirapalli, between August 2015 and December 2015, who were on maintenance dialysis. Fasting serum prolactin level was measured
in them to assess the presence of hyperprolactinemia. It was a prospective descriptive cross-sectional study. Quantitative determination of serum
prolactin was done by fully automated bidirectionally interfaced chemiluminescent immunoassay.
Results: Among the 50 CKD patients, 28 patients had raised serum prolactin levels. According to Statistical analysis of data using t-test, there is a
significant association between increased serum prolactin levels and presence of CKD.
Conclusion: CKD is associated with increased serum levels of hormone prolactin (hyperprolactinemia).
â€¢â€ƒHyperprolactinemia could be detected in 56% of patients with CKD
Keywords: Serum prolactin, Chronic kidney disease, Hypertension.
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