COMPARISON IN BENEFITS OF HERBAL MOUTHWASHES WITH CHLORHEXIDINE MOUTHWASH: A REVIEW

  • Renuka Selvakumar
  • Muralidharan Np

Abstract

Objective: To discuss the benefits of herbal mouthwashes with the standard chlorhexidine mouthwash. This review is conducted to explore the benefits of herbal mouthwashes.

Methods: Many herbal extracts are now available as mouthwash for maintaining the good oral hygiene. Plaque accumulation and increase in oral micro- organisms are the main factors for poor oral hygiene. Herbal extracts such as German chamomile, Terminalia chebula, Aloe vera, Green tea, peppermint satva, turmeric, neem, triphala, pomegranate extracts, guava extract, propolis, alum, darim leaves, mulethi, etc., are similar to chlorhexidine in plaque control and gingivitis reduction. Many herbal mouthwashes contain herbs with anti-microbial property such as neem, yavani satva, nagavalli, Gandhapura taila, pilu, Bibhitaka, Ocimum, Echinacea, Chameli leaves, etc. Many herbs are with anti-inflammatory and anti-oxidant property such as neem, clove, triphala (combination of amalaki, haritaki, and vibhitaki), tulsi, grapefruit, celery, licorice, katha, spearmint, and chamomile essential oil. Some herbal mouthwash with chamomile extract kills some skin pathogens such as staphylococcus and Candida species. Mixture of Staphysagria, Chamomilla, Echinacea, Plantago, Ocimum, and Cistus extracts used as mouth wash which was is better than chlorhexidine in reducing salivary mutans streptococcicount. Hence usage of herbal mouthwash will enhance the oral hygiene comparatively with chlorhexidine mouthwash without any adverse effects.

 Result: Though herbal mouthwashes has the ability to maintain good oral hygiene on daily basis, but still it is less effective than chlorhexidine mouthwash during treatments like gingivitis, periodontitis, trauma, etc.

 Conclusion: Besides the disadvantages, chlorhexidine mouthwash plays effective role during dental treatments on short term usage. Herbal mouthwashes are suitable for maintaining good oral prophylaxis. Many programs have to be conducted to make them aware about mouthwashes in their oral hygiene.

Keywords: Chlorhexidine, Herbal, Mouthwash, Oral hygiene, Prophylaxis.

References

1. Gupta D, Nayan S, Tippanawar HK, et al. Are herbal mouthwash efficacious over chlorhexidine on the dental plaque? Pharmacognosy Research. 2015;7(3):277-281. doi:10.4103/0974-8490.155874.
2. Loe H, Theilade E, Jensen SB. Experimental gingivitis in man. J Periodontol. 1965; 36:177-87.
3. Addy M. The use of antiseptics in periodontal therapy. In: Lindhe J, Karring T, Lang NP, editors. Clinical Periodontology and Implant Dentistry. 4th ed. New Delhi: Jaypee Brothers Medical Publishers (P) Ltd; 2003. p.
4. Lyle DM. Chemotherapeutics and Topical Delivery Systems. In: Wilkins EM, editor. Clinical Practice of the Dental Hygienist. 9th ed. Philadelphia: Wolters Kluwer Company; 2005. p. 439.
5. Dr. Gautam Biswas [1], Dr. Anup N. [2], Dr Siddharth Acharya [3], Dr. Himanshu Kumawat [3], Dr. Preeti Vishnani [3], Dr. Swasti Tambi [3]. Evaluation of the Efficacy Of 0.2% Chlorhexidine versus Herbal Oral Rinse on Plaque Induced Gingivitis- A Randomized Clinical Trail. IOSR Journal of Nursing and Health Science (IOSR-JNHS) e-ISSN: 2320–1959.p- ISSN: 2320–1940 Volume 3, Issue 2 Ver. V (Mar-Apr. 2014), PP 58-63.
6. Rao NJ, Subhas KR, Kumar KS. Role of Phytotherapy in gingivitis; a review. J Pharmacol. 2012;8:1–5.
7. Aspalli S, Shetty VS, Devarathnamma MV, Nagappa G, Archana D, Parab P. Evaluation of antiplaque and antigingivitis effect of herbal mouthwash in treatment of plaque induced gingivitis: A randomized, clinical trial. Journal of Indian Society of Periodontology. 2014;18(1):48-52. doi:10.4103/0972-124X.128208.
8. Ranjan Malhotra, Vishakha Grover, Anoop Kapoor, Divya Saxena. Comparison of the effectiveness of a commercially available herbal mouthrinse with chlorhexidine gluconate at the clinical and patient level. Journal of Indian Society of Periodontology 2011; 15(4); 349- 352. 

9. Mhaske M, Samad BN, Jawade R, Bhansali A. Chemical agents in control of dental plaque in dentistry: An overview of current knowledge and future challenges. Adv Appl Sci Res. 2012;3(1):268–72.
10. United States. CDC. GUIDELINE FOR PREVENTION OF SURGICAL SITE INFECTION, 1999. By Alicia J. Mangram, Teresa C. Horan, Michele L. Pearson, Leah C. Silver, and William R. Jarvis. CDC, Apr. 1999. Web. 13 Aug. 2012.
11. Genuit, Thomas, Grant Bochicchio, Lena M. Napolitano, Robert J. McCarter and Mary-Claire Roghman. "Prophylactic Chlorhexidine Oral Rinse Decreases Ventilator-Associated Pneumonia in Surgical ICU Patients." Surgical Infections March 2001, 2(1): 5-18. doi:10.1089/109629601750185316.
12. Jenkins S, Addy M, Wade W (August 1988). "The mechanism of action of chlorhexidine. A study of plaque growth on enamel inserts in vivo". J. Clin. Periodontol. 15 (7): 415–24. doi:10.1111/j.1600-051X.1988.tb01595.x. PMID 318306.
13. Leikin, Jerrold B.; Paloucek, Frank P., eds. (2008), "Chlorhexidine Gluconate", Poisoning and Toxicology Handbook(4th ed.), Informa, pp. 183–184.
14. Health Organization. WHO Guidelines on Hand Hygiene in Health Care. WHO, 2009. Web. 13 Aug. 2012.
15. Mohammadi, Z. and P. V. Abbott. "The Properties and Applications of chlorhexidine in Endodontics." International Endodontic Journal 42.4 (2009): 288-302.
16. Hibbard J. Analysis comparing the antimicrobial activity and safety of current antiseptics: a review. Journal of Infusion Nursing 2005; 28(3): 194-207.
17. Mathur, Setu, Tanu Mathur, Rahul Srivastava, and Rohit Khatri. "Chlorhexidine: The Gold Standard in Chemical Plaque Control." National Journal of Physiology, Pharmacy & Pharmacology 1.2 (2011): 45-50.


18. Zadik Y (December 2008). "Algorithm of first-aid management of dental trauma for medics and corpsmen". Dent Traumatol 24 (6): 698–701. doi:10.1111/j.1600-9657.2008.00649.x. PMID 19021668.
19. Zadik Y, Yitschaky O, Neuman T, Nitzan DW (July 2011). "On the self-resolution nature of the buccal bifurcation cyst". J. Oral Maxillofac. Surg. 69 (7): e282–4. doi:10.1016/j.joms.2011.02.124. PMID 21571416.
20. Mittal P, Gupta V, Kaur G, Garg AK, Singh A. Phytochemistry and pharmacological activities of Psidium guajava: A Review. Int J Pharm Sci Res 2010; 1(9): 9-19.
21. Vasconcelos LC, Sampaio FC, Sampaio MC, Pereira Mdo S, Higino JS, Peixoto MH. Minimum inhibitory concentration of adherence of Punica granatum Linn (pomegranate) gel against S. mutans, S. mitis and C. albicans. Braz Dent J. 2006; 17(3):223-227.
22. Seeram NP, Adams LS, Henning SM, Nio Y, Zhang Y, Nair MG et al. In vitro antiproliferative, apoptotic and antioxidant activities of punicalagin, ellagic acid and a total pomegranate tannin extract are enhanced in combination with other polyphenols as found in pomegranate juice. J Nutr Biochem 2005; 16(6):360-367.
23. Chidambara Murthy KN, Jayaprakasha GK, Singh RP. Studies on antioxidant activity of pomegranate (Punica granatum) peel extract using in vivo models. J Agric Food Chem 2002; 50(17): 4791-4795.
24. Battino M, Bullon P, Wilson M, Newman H. Oxidative injury and inflammatory periodontal diseases: the challenge of antioxidants to free radicals and reactive oxygen species. Crit Rev Oral Biol Med 1999; 10(4):458-476.
25. Menezes SM, Cordeiro LN, Viana GS. Punica granatum (pomegranate) extract is active against dental plaque. J Herb Pharmacother 2006; 6(2):79-92.
26. Dr. Bhavna Jhakukreja and Dr. Vidya dodwad.Herbal mouthwashes – a gift of nature. International Journal of Pharma and Bio Sciences. Vol-3; issue 2; April-June 2012; 46-52.
27. Biswas NP, Biswas AK. Evaluation of some leaf dusts as grain protectant against rice weevil Sitophilus oryzae (Linn). Environ Ecol 2005; 23(3): 485–488.
28. Weiss EI, Lev-Dor R, Kashamn Y, Goldhar J, Sharon N, Ofek I. Inhibiting interspecies coaggregation of plaque bacteria with a cranberry juice constituent. J Am Dent Assoc 1998. 129:1719-1723.
29. Walsh LJ. Preventive dentistry for the general dental practitioner. Aust Dent J 2000; 45:76-82.
30. Farah CS, MacIntosh L, MacCollough LJ. Mouthwashes. Australian 2009:32(6); 162-164.
31. Agarwal P, Nagesh L, Murlikrishnan Evaluation of the antibacterial activity of various concentrations of tulsi (Ocimum sanctum) extract against Streptococcus mutans: An in vitro study. Indian J Dent Res. 2010;21:357–9.
32. Vyas YK, Bhatnagar M, Sharma K. In vitroevaluation of antibacterial activity of an herbal dentrifice against Streptococcus mutans and Lactobacillus acidophilus. Indian J Dent Res. 2008;19:26–8.
33. Pourabbas R, Delazar A, Chitsaz MT. The effect of german chamomile mouthwash on dental plaque and gingival inflammation. Int J Pharm Res. 2005;2:105–9.
34. ELey BM. Antibacterial agents in the control of supragingival plaque :A review. Br Dent J. 1999;186:286–96.
35. Mehta S, Pesapathy S, Joseph M, Tiwari PK, Chawla S. Comparative evaluation of a herbal mouthwash (Freshol) with chlorhexidine on plaque accumulation, gingival inflammation, and salivary Streptococcus mutans growth. Journal of International Society of Preventive & Community Dentistry. 2013;3(1):25-28. doi:10.4103/2231-0762.115717.
36. Parwani SR, Parwani RN, Chitnis PJ, Dadlani HP, Prasad SVS. Comparative evaluation of anti-plaque efficacy of herbal and 0.2% chlorhexidine gluconate mouthwash in a 4-day plaque re-growth study. Journal of Indian Society of Periodontology. 2013;17(1):72-77. doi:10.4103/0972-124X.107478.
37. Gupta Rajendra Kumar 1, Gupta Devanand2, Bhaskar Dara John2, Yadav Ankit3, Obaid Khursheed4 , Mishra Sumit5 . Preliminary efficacy of aloe vera mouthwash on 4 day plaque re-growth model: Randomized control trial.Ethiop J Health Sci. Vol. 24, No. 2 April 2014. DOI:http://dx.doi.org/10.4314/ejhs.v24i2.6.
38. Abdolhosein Moghbel 1*, Ahmad Farjzadeh 2, Nasrin Aghel 3, Homayoon Agheli 4, Nafiseh Raisi 1 .The Effect of Green Tea on Prevention of Mouth Bacterial Infection, Halitosis, and Plaque Formation on Teeth. Iranian Journal of Toxicology Volume 5, No 14, Autumn 2011.
39. Neeraja R, Anantharaj A, Praveen P, Karthik V, Vinitha M. The effect of povidone-iodine and chlorhexidine mouth rinses on plaque Streptococcus mutans count in 6- to 12-year-old school children: An in vivo study. J Indian Soc Pedod Prev Dent 2008;26, Suppl S1:14-8.
40. Prasad KARV, John S, Deepika V, Dwijendra KS, Reddy BR, Chincholi S. Anti-Plaque Efficacy of Herbal and 0.2% Chlorhexidine Gluconate Mouthwash: A Comparative Study. Journal of International Oral Health : JIOH. 2015;7(8):98-102.
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Selvakumar, R., and M. Np. “COMPARISON IN BENEFITS OF HERBAL MOUTHWASHES WITH CHLORHEXIDINE MOUTHWASH: A REVIEW”. Asian Journal of Pharmaceutical and Clinical Research, Vol. 10, no. 2, Feb. 2017, pp. 3-7, doi:10.22159/ajpcr.2017.v10i2.13304.
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