A CASE REPORT OF PHENYTOIN AND CARBAMAZEPINE CROSS-REACTIVITY

  • Bhuvana K Associate Professor, Department of Pharmacology, Sri Devaraj Urs Medical College, Sri Devaraj University of Higher Education and Research Tamaka, Kolar, Karnataka, India
  • Sarala N Professor and HOD, Department of Pharmacology, Sri Devaraj Urs Medical College, Sri Devaraj University of Higher Education and Research, Tamaka, Kolar. Karnataka, India
  • Venkatarathnamma P N Professor, Department of Medicine, Sri Devaraj Urs Medical College, Sri Devaraj University of Higher Education and Research Tamaka, Kolar. Karnataka, India
  • T N Kumar Professor and HOD, Department of Pharmacology, Sree Narayana Institute of Medical Sciences, Chalakka, Ernakulam, Kerala, India

Abstract

ABSTRACT
A case report of cross-reactivity between phenytoin and carbamazepine, a 63-year-old male patient was prescribed phenytoin for generalized seizures
and on the 15
day of therapy developed generalized maculopapular eruptions. Phenytoin was discontinued, and carbamazepine was administered.
After 28 days, he developed fever, generalized rashes with ulcers in the oral cavity. Carbamazepine was withdrawn, and the patient was treated
symptomatically.
th
Keywords: Phenytoin, Carbamazepine, Cross-reactivity.

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How to Cite
K, B., S. N, V. N, and T. Kumar. “A CASE REPORT OF PHENYTOIN AND CARBAMAZEPINE CROSS-REACTIVITY”. Asian Journal of Pharmaceutical and Clinical Research, Vol. 9, no. 14, Oct. 2016, pp. 7-8, doi:10.22159/ajpcr.2016.v9s2.13599.
Section
Case Study(s)