• Anand V Nimbal
  • Vikas C Desai
  • Shardha Bai Rathod


Objective: Diabetes mellitus is the leading health problem across the world. It is associated with several complications such as retinopathy, neuropathy,
oral manifestations, chronic macrovascular and microvascular complications. Our objective is to compare these oral manifestations in controlled and
uncontrolled diabetic patients.
Methods: A study was conducted on total of 100 diabetic patients. The patients were divided into two groups: Group I (n=50) consists of controlled
diabetic patients and Group II (n=50) consists of uncontrolled diabetic patients. Before, the start of the study proper oral examination was done
for both the groups. Samples were collected and were subjected to microbial examination. Comparison between both the groups was done for oral
Results: It showed that uncontrolled diabetic patients had a higher incidence of oral manifestations such as hyposalivation, parotid enlargement,
burning sensation of mouth, taste alterations, sialorrhea, dental carries, and microbial lesions than controlled diabetes patients.
Conclusion: Uncontrolled diabetic patients had higher risk of oral manifestations than controlled diabetic individuals.
Keywords: Diabetes mellitus, Retinopathy, Neuropathy, Oral manifestations, Periodontitis, Hyposalivation.


1. Bajaj S, Prasad S, Gupta A, Singh VB. Oral manifestations in Type-2 diabetes and related complications. Indian J Endocrinol Metab 2012;16(5):777-9.
2. Brian L, Thomas W. Periodontal disease and diabetes in young adults. J Am Med Assoc 1960;172(8):776-8.
3. Gandara BK, Morton TH. Non-periodontal oral medications of diabetes: A framework for medical care providers. Diabetes Spectr 2011;24(4):199-205.
4. Whelton H. Functions of saliva. In: Edgar M, Dawes C, O’Mullane D, editors. Saliva and Oral Health. 3rd ed. London: British Dental Association; 2004. p. 3.
5. Dale BA, Fredericks LP. Antimicrobial peptides in the oral environment: Expression and function in health and disease. Curr Issues Mol Biol 2005;7(2):119-33.
6. Russotto SB. Asymptomatic parotid gland enlargement in diabetes mellitus. Oral Surg Oral Med Oral Pathol 1981;52(6):594-8.
7. Murrah VA, Crosson JT, Sauk JJ. Parotid gland basement membrane variation in diabetes mellitus. J Oral Pathol 1985;14(3):236-46.
8. Gibson J, Lamey PJ, Lewis M, Frier B. Oral manifestations of previously undiagnosed non-insulin dependent diabetes mellitus. J Oral Pathol Med 1990;19(6):284-7.
9. Zachariasen RD. Diabetes mellitus and xerostomia. Compendium 1992;13(4):314, 316, 318-22.
10. Odds FC. Candida and Candidiasis. 2nd ed. London, Philadelphia, PA: Bailliére Tindall; 1988.
11. Olsen I. Denture stomatitis. Occurrence and distribution of fungi. Acta Odontol Scand 1974;32(5):329-33.
12. Farman AG, Nutt G. Oral Candida, debilitating disease and atrophic lesions of the tongue. J Biol Buccale 1976;4(3):203-26.
13. Lamey PJ, Darwaza A, Fisher BM, Samaranayake LP, Macfarlane TWFrier BM. Secretor status, candidal carriage and candidal infection in patients with diabetes mellitus. J Oral Pathol 1988;17(7):354-7.
14. Birman EG, Silveira FR, Sampaio MC. Study of oral mucosal lesions in geriatric patients. Rev Fac Odontol Univ Antioq 1991;19(3):173-5.
15. Mealey BL, Oates TW; American Academy of Periodontology. Diabetes mellitus and periodontal diseases. J Periodontol 2006;77(8):1289-303.
16. Lalla RV, D’Ambrosio JA. Dental management considerations for the patient with diabetes mellitus. J Am Dent Assoc 2001;132(10):1425-32.
17. Azodo CC. Current trends in the management of diabetes mellitus: The dentist’s perspective. Benign J Postgrad Med 2009;11(1):113-29.
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How to Cite
Nimbal, A., V. Desai, and S. Rathod. “A COMPARATIVE STUDY IN THE DIABETES MELLITUS PATIENTS FOR ORAL MANIFESTATION AT TERTIARY CARE HOSPITAL IN NORTH KARNATAKA”. Asian Journal of Pharmaceutical and Clinical Research, Vol. 9, no. 9, Dec. 2016, pp. 305-7, doi:10.22159/ajpcr.2016.v9s3.14696.
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