TO STUDY THE DRUG USE PATTERN IN PRIMARY OPEN ANGLE GLAUCOMA IN A TERTIARY CARE TEACHING

  • Deepalatha C
  • Leela Pratyusha Mb

Abstract

Objective: To study the drug utilization pattern in patients suffering from primary open-angle glaucoma (POAG) in a tertiary care teaching hospital.

Methods: It is a prospective study done on 50 patients of POAG (comprising of individuals belonging to any age group). This study was carried for a period of 2-month, and the data included patient’s demographic details and the drugs prescribed. Data were analyzed for drug use pattern.

Results: After screening the prescriptions of patients, it was found out that out of total 50 prescriptions, 30 were males, and 20 were females. Out of

50 prescriptions, prostaglandins (58%) were most commonly prescribed. β-blockers (16%) were also prescribed. Fixed dose combination constituted

60% of the prescriptions. Instructions about the route, frequency, and duration of treatment were present in all prescriptions. Drugs prescribed by their generic names were 18.75% and about 81.25% of the drugs were prescribed by their brand names.

Conclusions: Fixed drug combination of timolol and dorzolamide was the most frequently prescribed combination. Prescribers must be aware of

importance of prescribing drugs with generic names.

Keywords: Primary open-angle glaucoma, Intraocular pressure, Fixed dose combination.

References

1. Yadav AK, Patel V. Drug use in primary open angle glaucoma: A
prospective study at a tertiary care teaching hospital. Indian J Pharmacol 2013;45(2):117-20.
2. The Japan Glaucoma Society. Guidelines for Glaucoma. 2nd ed. Savona: Editrice Dogma; 2006.
3. Yanolff M, Duker JS, editors. Ophthalmology. London: Mosby
International Ltd.; 1999.
4. Khurana AK. Comprehensive Ophthalmology. 5th ed. India: New Age International; 2012.
5. Pan Y, Varma R. Natural history of glaucoma. Indian J Ophthalmol
2011;59 Suppl: S19-23.
6. Quigley HA, Broman AT. The number of people with glaucoma worldwide in 2010 and 2020. Br J Ophthalmol 2006;90(3):262-7.
7. George R, Ve RS, Vijaya L. Glaucoma in India: Estimated burden of disease. J Glaucoma 2010;19(6):391-7.
8. Agarwal HC, Gulati V, Sihota R. Dr. Rajendra Prasad Centre for Ophthalmic Sciences. New Delhi, India: All India Institute of Medical Sciences.
9. Saepudin GB. Drug utilisation 90% (DU 90%) profile of antibiotic for treatment of hospitalised patients in Yogyakarta. J Llmaih Farmasi
2008;5:42-8.
10. Melrose D. Double deprivation public and private drug distribution from the perspective of the third world’s poor. World Dev 1983;11:181-6.
11. Sharma R, Khajuria R, Sharma P, Sadhotra P, Kapoor B, Kohli K,
et al. Glaucoma therapy: Prescribing pattern and cost analysis. JK Sci
2004;6:88-92.
12. Nies AS. Principles of therapeutics. In: Gilman AG, Rall TW, Nies AS, editors. The Pharmacological Basis of Therapeutics. 8th ed. New York: Pergamon Press; 1990. p. 62-83.
13. Pradhan SC, Shewade DG, Tekur U, Zutshi S, Pachiappan D, Dey AK, et al. Changing pattern of antimicrobial utilization in an Indian teaching hospital. Int J Clin Pharmacol Ther Toxicol 1990;28(8):339-43.
14. Atanasova I, Terziivanov D. Investigation on antibiotics in a hospital for a one-year period. Int J Clin Pharmacol Ther 1995;33(1):32-3.
15. Biswas NR, Jindal S, Siddiquei MM, Maini R. Patterns of prescription and drug use in ophthalmology in a tertiary hospital in Delhi. Br J Clin Pharmacol 2001;51(3):267-9.
16. Minocha KB, Bajaj S, Gupta K. A clinic pharmacological study of out- patient prescribing pattern of dermatological drugs in an Indian tertiary hospital. Indian J Pharmacol 2000;32:384-5.
17. Maini R, Verma KK, Biswas NR, Agrawal SS. Drug utilization study in dermatology in a tertiary hospital in Delhi. Indian J Physiol Pharmacol
2002;46(1):107-10.
18. Karunakaran R, Sadanandan SP. Computational insights on novel rock-1 inhibitors from marine compounds towards antiglaucoma therapeutics. Int J Pharm Clin Res 2016;8(9):1269-73.
Statistics
402 Views | 389 Downloads
How to Cite
C, D., and L. P. Mb. “TO STUDY THE DRUG USE PATTERN IN PRIMARY OPEN ANGLE GLAUCOMA IN A TERTIARY CARE TEACHING”. Asian Journal of Pharmaceutical and Clinical Research, Vol. 10, no. 2, Feb. 2017, pp. 198-00, doi:10.22159/ajpcr.2017.v10i2.15172.
Section
Original Article(s)

Most read articles by the same author(s)