STUDY OF PRESCRIBING PATTERN AND USE OF ANTIBIOTIC IN THE MANAGEMENT OF WOUND INFECTION
Objective: The main objective of the study is to estimate the demographic details of patients with various wound infection and to observe the various
organism causing infections and also to analyze the prescribing pattern of antibiotic used in wound infection.
Methods: This is a prospective observational study to evaluate the prescribing pattern of antibiotics in the Department of Surgery. The study was
conducted for 4 months (April 2016-July 2016), the information was collected from the case sheets, and the data were analyzed using Microsoft Excel.
Results: In this study, males were higher than females consisting of 64.5% of the total sample size. In wound infection, diabetic foot ulcer was
found to be a major problem. It can be observed that antibiotics were prescribed for all of the patients with cefotaxime being prescribed the most as
monotherapy. Cefotaxime+metronidazole were commonly prescribed as dual therapy. Multivitamins, antiulcerants were other major drugs provided
in the supportive care. With reference to the culture sensitivity test, the major organism isolated was Staphylococcus aureus.
Conclusion: An important consideration is needed in prescribing antibiotic therapy. The utilization of culture sensitivity studies are limited and
most antibiotic selection is empirical, so proper evaluation and monitoring is needed by the health-care professionals to select the appropriate one to
promote the rational use of antibiotics.
Keywords: Diabetic foot ulcer, Wound sepsis, Burns, Surgical site infection, Antibiotics.
Occult Aminoglycoside resistance in Pseudomonas aeruginosa:
Epidemiology and implications for therapy and control. J Infect Dis
2. Gonzales R, Bartlett JG, Besser RE, Cooper RJ, Hickner JM,
Hoffman JR, et al. Principles of appropriate antibiotic use for treatment
of acute respiratory tract infections in adults: Background, specific
aims, and methods. Ann Emerg Med 2001;37(6):690-7.
3. Heinzelmann M, Scott M, Lam T. Factors predisposing to bacterial
invasion and infection. Am J Surg 2002;183(2):179-90.
4. Recognition and Management of Wound infection. Available from:
http://www.worldwidewounds.com/2004/january/collier/managementof-wound-infections.html, www.[Lastaccessed on 2016 Oct 17].
5. White RJ, Cooper R, Kingsley A. Wound colonization and infection:
The role of topical antimicrobials. Br J Nurs 2001;10(9):563-78.
6. Brook I, Frazier EH. Aerobic and anaerobic bacteriology of wounds
and cutaneous abscesses. Arch Surg 1990;125(11):1445-51.
7. Kingsley A. A proactive approach to wound infection. Nurs Stand
2001;15(30):50-4, 56, 58.
8. Collier M. Universal concepts. J Wound Care 2001;10(7):249.
9. Cutting KF, White R. Defined and refined: Criteria for identifying
wound infection revisited. Br J Community Nurs 2004;9(3):S6-15.
10. Nagoba BS, Selkar SP, Mule JB. Irrigating methicillin-resistant
Staphylococcus aureus-colonized and - Infected chronic wounds - Why
use tap water? Int Wound J 2013;12(5):605.
11. Oâ€™Meara S, Cullum C, Majid M, Sheldon T. IR7: A systematic review
of systemic and topical antimicrobial agents used in the prevention and
treatment of chronic wounds. Value Health 1999;2(5):359.
12. Thomas Z. Study on drug utilization, prescribing pattern of antibiotic in the management of diabetic foot ulcer. IJIPSR 2015;3(8):1037-49.
13. Immranuddin M, Asfin M, Sruthi VV, Deshpande S, Kumar TP,
Reddy MV, et al. cost analysis and prescribing patterns of antibiotic in
post operative surgery patients. IAJPR 2015;12(11):2231-6876.
14. Dipiro JT, Talbert RL, Yee GC, Matzke GR, Wells BG, Michaelposey L.
Pharmacotherapy: A Pathophysiologic Approach. 8
ed. United States of America: McGraw-hill Companies; 2011. p. 16.th
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