ANTIBACTERIAL ACTIVITY OF AQUEOUS ALCOHOLIC EXTRACT OF ABUTILON INDICUM AERIAL PARTS AGAINST E .FAECALIS – AN INVITRO STUDY

  • Jannathul FERDIOZ Department of Dental Surgery, Saveetha Dental College and Hospitals, Chennai, Tamil Nadu, India.
  • Anitha Roy Department of General Pharmagology, Faculty of Pharmacology, Saveetha Dental College and Hospitals, Chennai, Tamil Nadu, India

Abstract

Objective: To evaluate the antibacterial activity of the aqueous alcoholic extracts of Abutilon indicum aerial parts against Enterococcus faecalis.

Methods: Agar well diffusion assay, as well as microbroth dilution assays, were used for determination of antibacterial activity. The assay was done in
triplicate, and chlorhexidine 0.2% was used as the control.

Results: Different concentrations (200, 400, and 800 mg/mL) of the ethyl acetate extract of A. indicum aerial parts showed dose-dependant
antibacterial activity. The maximum zone of inhibition was 30 mm at the maximum concentration used (800 mg/mL), and the minimum inhibitory
concentration/minimum bactericidal concentration was found to be 200 mg/mL.

Conclusion: This study suggests that the aqueous alcoholic extract of A. indicum aerial parts contains promising antibacterial substances which are
having activity against E. faecalis. E. faecalis being one of the major threats for root canal failure during endodontic treatment; plants with antibacterial
activity against E. faecalis will be promising.

Keywords: Abutilon indicum, Enterococcus faecalis, Antibacterial activity, Root canal failure.

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FERDIOZ, J., and A. Roy. “ANTIBACTERIAL ACTIVITY OF AQUEOUS ALCOHOLIC EXTRACT OF ABUTILON INDICUM AERIAL PARTS AGAINST E .FAECALIS – AN INVITRO STUDY”. Asian Journal of Pharmaceutical and Clinical Research, Vol. 10, no. 5, May 2017, pp. 80-81, doi:10.22159/ajpcr.2017.v10i5.15636.
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