• Mohammad Suhaib J.N Medical College, Aligarh Muslim University
  • Farida Ahmad
  • Mohammed Ahmad


Objective:The purpose of the study was to find out the pattern of antimicrobial prescription among dental practitioners in a tertiary care centre in North India.

 Methods:100 prescriptions of the patients attending the various dental outpatient departments of Ziauddin Ahmed Dental College, Aligarh Muslim University were collected and tabulated between January 2016 to June 2016. An observational study was done on the obtained prescriptions on various aspects like dental pathology for which antimicrobial were prescribed, antimicrobial agents used for management of acute and chronic conditions along with their dose and duration. Compliance of the patients during therapy and  adverse effects associated with the regimen was also taken into consideration and the final data was expressed as counts and percentages.

Results: Out of a total of 100 patients 54 (54.0%) were males while females were numbered as 46 (42.0%) with maximum distribution of the patients between 31-40 years. On analysis the most commonly presented dental condition for which antimicrobials were prescribed were Acute/Chronic periodontitis (48%), Acute/Chronic gingivitis (32%), Caries (11%), Post RCT (4%), Pericoronitis (3%), Oral trauma (1%) and other condition (1%). For the management of above conditions  antimicrobials were the most extensively used agents which were prescribed for only 3-5 days which may not be sufficient, followed by analgesics and antimicrobial mouthwashes. Among the antimicrobials used, most frequently used agents were Amoxycillin (50%) followed by Ornidazole (21%), Ofloxacin (20%), Doxycycline (16%), Cefixime (9%) and Ciprofloxacin (3%) used either alone or in combination for the management of acute and chronic conditions. Only two patients were advised for culture & sensitivity tests prior to antimicrobial therapy because of non compliance of patients. Majority (74%) of patients completed the prescribed regimen of antimicrobials while 7 patients reported adverse drug reactions(ADRs), among which most common  were nausea and vomiting.

Conclusions: In our study we found that the periodontal diseases were the most frequently reported conditions followed by acute/chronic gingivitis for which antimicrobials were prescribed while Amoxycillin and Ornidazole were the most commonly used antimicrobials for the management of various acute and chronic dental conditions, but were prescribed without culture & sensitivity in most cases. 7% patients reported ADRs. To conclude appropriate measures are to be promoted for rational prescribing and ADR reporting.

Keywords: Amoxicillin, Dental, Antimicrobials, infections, Prescription pattern.

Author Biography

Mohammad Suhaib, J.N Medical College, Aligarh Muslim University
Senior resident


1. Dar-Odeh N, Ryalat S, Shayyab M, Abu-Hammad O. Analysis of clinical records of dental patients attending Jordan University Hospital: Documentation of drug prescriptions and local anesthetic injections. Ther Clin Risk Manag 2008;4(5):1111-7.
2. Lewis MA. Why we must reduce dental prescription of antibiotics: European Union Antibiotic Awareness Day. Br Dent J 2008;205(10):537-8.
3. Salako NO, Rotimi VO, Adib SM, Al-Mutawa S. Pattern of antibiotic prescription in the management of oral diseases among dentists in Kuwait. J Dent 2004;32(7):503-9.
4. Swift JQ, Gulden WS. Antibiotic therapy – Managing odontogenic infections. Dent Clin North Am 2002;46(4):623-33, vii.
5. Bennadi D. Antimicrobial stewardship - An alarming call in dentistry. Int J Pharm Pharm Sci 2014;6(2):46-9.
6. Weber JT, Courvalin P. An emptying quiver: Antimicrobial drugs and resistance. Emerg Infect Dis 2005;11(6):791-3.
7. Standing Medical Advisory Committee. Sub-Group on Antimicrobial Resistance. The Path of Least Resistance. London: Stationery Office; 1998.
8. Craig WA, Uman SJ, Shaw WR, Ramgopal V, Eagan LL, Leopold ET. Hospital use of antimicrobial drugs. Survey at 19 hospitals and results of antimicrobial control program. Ann Intern Med 1978;89:793-5.
9. Dar-Odeh NS, Abu-Hammad OA, Al-Omiri MK, Khraisat AS, Shehabi AA. Antibiotic prescribing practices by dentists: A review. Ther Clin Risk Manag 2010;6:301-6.
10. WHO. Studies in Drug Utilization. European Series No. 8. Copenhagen: WHO Regional Publications; 1979.
11. Al-Haroni M, Skaug N. Incidence of antibiotic prescribing in dental practice in Norway and its contribution to national consumption. J Antimicrob Chemother 2007;59(6):1161-6.
12. Gour PR, Kohli S, Advani U. Prescription pattern of antimicrobial agents by dental practitioners: A questionnaire based study. Int J Basic Clin Pharmacol 2013;2(3):311-4.
13. Drug Prescribing for Dentistry. Dental Clinical Guidance. 2nd ed. August, 2011. Available from: [Last accessed on 2013 Feb 15].
14. Antibiotic Prescribing Guidelines for Dentists. NHS Cambridge Shire and Peterborough Clinical Commissioning Group. Available from: [Last accessed on 2013 Feb 15].
15. Al-Haroni M, Skaug N. Knowledge of prescribing antimicrobials among Yemeni general dentists. Acta Odontol Scand 2006;64(5):274-80.
16. Palmer NA, Pealing R, Ireland RS, Martin MV. A study of therapeutic antibiotic prescribing in National Health Service general dental practice in England. Br Dent J 2000;188(10):554-8.
17. Vessal G, Khabiri A, Mirkhani H, Cookson BD, Askarian M. Study of antibiotic prescribing among dental practitioners in Shiraz, Islamic Republic of Iran. East Mediterr Health J 2011;17(10):763-9.
18. Kaur SP, Rao R, Nanda S. Amoxicillin: A broad spectrum antibiotic. Int J Pharm Pharm Sci 2011;3(3):30-7.
19. Marsh PD, Martin MV. Oral Microbiology. 4th ed. Oxford: Wright; 1999. p. 210-1.
20. Lacey RW, Lord VL, Howson GL, Luxton DE, Trotter IS. Double-blind study to compare the selection of antibiotic resistance by amoxycillin or cephradine in the commensal flora. Lancet 1983;2:529-32.
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How to Cite
Suhaib, M., F. Ahmad, and M. Ahmad. “PRESCRIPTION PATTERN OF ANTIMICROBIAL AGENTS AMONG DENTAL PRACTITIONERS IN A TERTIARY CARE CENTRE IN NORTH INDIA”. Asian Journal of Pharmaceutical and Clinical Research, Vol. 10, no. 4, Apr. 2017, pp. 192-5, doi:10.22159/ajpcr.2017.v10i4.16525.
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