USE OF TISSUE DOPPLER IMAGING TO DETECT RIGHT VENTRICULAR MYOCARDIAL DYSFUNCTION IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE


Jyothi Samanth, Padmakumar R, Ashwinikumar Mohapatra, Krishnananda N, Navin Patil, Kartthik Rao, Vidya Nayak, Balaji Ommurugan, Dipanjan Bhattachariya, Rahul Kotian

Abstract


Objective: To determine the utility of tissue Doppler imaging (TDI) in detecting early right ventricle (RV) myocardial dysfunction, given its prognostic implications in patients with chronic obstructive pulmonary disease (COPD).

Methods:  A prospective case-control study was carried out involving 36 COPD patients in an acute exacerbated state as cases and 34 healthy subjects serving as controls. Each subject underwent a baseline echocardiography using various methods ranging from m-mode and 2-dimensional measures for analyzing RV geometry to strain and strain rate using Tissue Doppler Imaging to measure RV deformation. The cases underwent a subsequent echocardiogram 1month later once the respiratory symptoms subsided.

Results: A significant difference was observed in RV tissue annular velocities ( E’, A’, S) between cases and the controls at baseline. However no significant increase was observed in tissue annular velocities among cases during remission states from baseline. Peak systolic strain in COPD group was significantly reduced in comparison to controls, but not significantly increased during remission when compared to baseline in cases. FEV1/VC did not bear any significant correlation with RV strain. Tei index had a negative linear correlation with peak systolic strain of RV, which was statistically significant.

Conclusion: TDI parameters revealed that RV dysfunction remains unaltered even in remission state of COPD, despite pulmonary arterial pressure normalizing. In light of it bearing a negative prognosis in COPD, RV dysfunction merits assessment in COPD patients, both in acute exacerbations as well as in remission.

 

 


Keywords


Strain rate, Tissue annular velocity, Doppler, Right ventricle geometry, Case-control

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About this article

Title

USE OF TISSUE DOPPLER IMAGING TO DETECT RIGHT VENTRICULAR MYOCARDIAL DYSFUNCTION IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE

Keywords

Strain rate, Tissue annular velocity, Doppler, Right ventricle geometry, Case-control

DOI

10.22159/ajpcr.2017.v10i6.17517

Date

01-06-2017

Additional Links

Manuscript Submission

Journal

Asian Journal of Pharmaceutical and Clinical Research
Vol 10 Issue 6 June 2017 Page: 118-124

Print ISSN

0974-2441

Online ISSN

2455-3891

Statistics

15 Views | 20 Downloads

Authors & Affiliations

Jyothi Samanth
Department of Cardiovascular Technology, School of Allied Health Sciences, Manipal University, Karnataka, India.
India

Padmakumar R
Department of Cardiology, KMC Manipal, Manipal University, Manipal, Karnataka, India.
India

Ashwinikumar Mohapatra
3Department of Pulmonary Medicine, KMC Manipal, Manipal University, Manipal, Karnataka, India.
India

Krishnananda N
Department of Cardiovascular Technology, School of Allied Health Sciences, Manipal University, Karnataka, India.
India

Navin Patil
Department of Pharmacology, KMC Manipal, Manipal University, Manipal, Karnataka, India.
India

Kartthik Rao
Department of Medicine, KMC Manipal, Manipal University, Manipal, Karnataka, India.
India

Vidya Nayak
Department of Cardiovascular Technology, School of Allied Health Sciences, Manipal University, Karnataka, India.
India

Balaji Ommurugan
Department of Pharmacology, KMC Manipal, Manipal University, Manipal, Karnataka, India.
India

Dipanjan Bhattachariya
Department of Pharmacology, KMC Manipal, Manipal University, Manipal, Karnataka, India.
India

Rahul Kotian
Department of Medical Imaging Technology, SOAHS, Manipal University, Manipal, Karnataka, India.
India


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