PROGNOSTIC BIOMARKERS IN TRIPLE NEGATIVE BREAST CANCER AS A POTENTIAL TARGET FOR FUTURE DRUG DISCOVERY


Mekhla Gupta, Sanjeev Kumar Gupta, Rajesh Kumar Singh, Seema Khanna

Abstract


Breast cancer is the most common malignancy in women globally, in which triple-negative breast cancer (TNBC) is more aggressive with poor prognosis and very less response to targeted hormone based treatment. It is a major cause of deaths among the women with breast cancer because of very few treatment options. The biomarkers could be a product of cancerous cell or molecule generated in response to cancer. It is used to understand the mechanism, prognosis, diagnosis as well as target for design and discovery of new drugs. The purpose of the study is to give a brief review on
markers of TNBC.


Keywords


Breast cancer, Triple-negative breast cancer, Biomarkers, Drug discovery, Diagnosis.

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About this article

Title

PROGNOSTIC BIOMARKERS IN TRIPLE NEGATIVE BREAST CANCER AS A POTENTIAL TARGET FOR FUTURE DRUG DISCOVERY

Keywords

Breast cancer, Triple-negative breast cancer, Biomarkers, Drug discovery, Diagnosis.

DOI

10.22159/ajpcr.2017.v10i6.17727

Date

01-06-2017

Additional Links

Manuscript Submission

Journal

Asian Journal of Pharmaceutical and Clinical Research
Vol 10 Issue 6 June 2017 Page: 24-28

Print ISSN

0974-2441

Online ISSN

2455-3891

Statistics

62 Views | 63 Downloads

Authors & Affiliations

Mekhla Gupta
Department of General Surgery, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India
India

Sanjeev Kumar Gupta
Department of General Surgery, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India
India

Rajesh Kumar Singh
Department of Dravyaguna, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.
India

Seema Khanna
Department of General Surgery, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.
India


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