EFFECT OF CURCUMA LONGA EXTRACT ON BIOFILM FORMATION BY STREPTOCOCCUS MUTANS


Gokul G, Geetha Rv

Abstract


Objective: To find the effect of Curcuma longa extract on biofilm formation by Streptococcus mutans.

Methods: The organism S. mutans was isolated from saliva sample using special media (Mutans - sanguis agar) and maintained in tryptone soya agar at 4°C in Department of Microbiology, Saveetha Dental College and Hospitals.

Results: From the study, we infer that 78.35% of inhibition of the biofilm formation is seen with 100 ug of curcumin extract. From the result, it is evident that curcumin has a very good inhibitory effect on S. mutans growth.

Conclusion: The study concludes the inhibitory action of curcumin on S. mutans by preventing biofilm formation.


Keywords


Curcuma, Streptococcus mutans, Biofilm.

| PDF |

References


Cvitkovitch DG, Li YH, Ellen RP. Quorum sensing and biofilm formation in Streptococcal infections. J Clin Invest 2003;112(11):1626-32.

Ferracane JL. Resin composite - State of the art. Dent Mater 2011;27(1):29-38.

Thomas JE, Gibson GR, Darboe MK, Dale A, Weaver LT. Isolation of Helicobacter pylori from human faeces. Lancet 1992;340(8829):1194-5.

Ogawa A, Furukawa S, Fujita S, Mitobe J, Kawarai T, Narisawa N, et al. Inhibition of Streptococcus mutans biofilm formation by Streptococcus salivarius Fru A. Appl Environ Microbiol 2011;77(5):1572-80.

Evans CE, Banso A, Samuel OA. Efficacy of some nupe medicinal plants against Salmonella typhi: An in vitro study. J Ethnopharmacol 2002;80(1):21-4.

Ahmad I, Mehmood Z, Mohammad F. Screening of some Indian medicinal plants for their antimicrobial properties. J Ethnopharmacol 1998;62(2):183-93.

Tayyem RF, Heath DD, Al-Delaimy WK, Rock CL. Curcumin content of turmeric and curry powders. Nutr Cancer 2006;55(2):126-31.

Bhavani Shankar TN, Sreenivasa Murthy V. Effect of turmeric (Curcuma longa) fractions on the growth of some intestinal and pathogenic bacteria in vitro. Indian J Exp Biol 1979;17(12):1363-6.

Arun N, Nalini N. Efficacy of turmeric on blood sugar and polyol pathway in diabetic albino rats. Plant Foods Hum Nutr 2002;57(1):41-52.

Jayaprakasha GK, Negi PS, Anandharamakrishnan C, Sakariah KK. Chemical composition of turmeric oil - A byproduct from turmeric oleoresin industry and its inhibitory activity against different fungi. Z Naturforsch C 2001;56(1-2):40-4.

Menon VP, Sudheer AR. Antioxidant and anti-inflammatory properties of curcumin. Adv Exp Med Biol 2007;595:105-25.

Panesar PS, Kumari S, Panesar R. Biotechnological approaches for the production of prebiotics and their potential applications. Crit Rev Biotechnol 2013;33(4):345-64.

Pandit S, Kim HJ, Kim JE, Jeon JG. Separation of an effective fraction from turmeric against Streptococcus mutans biofilms by the comparison of curcuminoid content and anti-acidogenic activity. Food Chem 2011;126(4):1565-70.

Clark AM. Natural products as a resource for new drugs. Pharm Res 1996;13(8):1133-44.

Cordell GA. Biodiversity and drug discovery - A symbiotic relationship. Phytochemistry 2000;55(6):463-80.

Song J, Choi B, Jin EJ, Yoon Y, Choi KH. Curcumin suppresses Streptococcus mutans adherence to human tooth surfaces and extracellular matrix proteins. Eur J Clin Microbiol Infect Dis 2012;31(7):1347-52.

Takahashi N, Nyvad B. The role of bacteria in the caries process: Ecological perspectives. J Dent Res 2010;90(3):294-303.

Baghaeian P, Sodagar A, Bahador A, Pourhajibagher M, Ahmadi B. Effect of addition of curcumin nanoparticles on antimicrobial property and shear bond strength of orthodontic composite to bovine enamel. J Dent Tehran Univ Med Sci 2016;13(5):373-82.

Moghadamtousi SZ, Kadir HA, Hassandarvish P, Tajik H, Abubakar S, Zandi K. A review on antibacterial, antiviral, and antifungal activity of curcumin. Biomed Res Int 2014;2014:186864.

Devaraj SD, Neelakantan P. Curcumin-pharmacological actions and its role in dentistry. Asian J Pharm Res Health Care 2014;6(1):19-22.

Neelakantan P, Jagannathan N, Nazar N. Ethnopharmacological approach in endodontic treatment: A focused review. Int J Drug Dev Res 2011;3(4):68-77.




About this article

Title

EFFECT OF CURCUMA LONGA EXTRACT ON BIOFILM FORMATION BY STREPTOCOCCUS MUTANS

Keywords

Curcuma, Streptococcus mutans, Biofilm.

DOI

10.22159/ajpcr.2017.v10i7.18161

Date

01-07-2017

Additional Links

Manuscript Submission

Journal

Asian Journal of Pharmaceutical and Clinical Research
Vol 10 Issue 7 July 2017 Page: 186-187

Print ISSN

0974-2441

Online ISSN

2455-3891

Statistics

112 Views | 173 Downloads

Authors & Affiliations

Gokul G
Department of Microbiolgy, Saveetha Dental College, Chennai, Tamil Nadu, India.
India

Geetha Rv
Department of Microbiology, Saveetha Dental College,Chennai, Tamil Nadu, India.
India


Article Tools


Email this article (Login required)
Email the author (Login required)

Refbacks

  • There are currently no refbacks.