PHYTOCHEMICAL STUDIES AND PHARMACOGNOSTICAL EVALUATION OF ZINGIBER CASSUMUNAR ROXB

  • Akshada Amit Koparde Department of Pharmaceutical Chemistry, Rajarambapu College of Pharmacy, Kasegaon, Sangli, Maharashtra, India.
  • Magdum Cs Department of Pharmaceutical Chemistry, Rajarambapu College of Pharmacy, Kasegaon, Sangli, Maharashtra, India.

Abstract

 

 Objective: Zingiber Cassumunar Roxb is a well known medicinal plant employed to cure various diseases were reported to possess good medicinal value in traditional system of medicine. The present investigation deals with microscopic, macroscopic and preliminary phytochemical investigation of rhizome to give clear standards for identification of the drug.

Method: For the microscopic evaluation, the powder was soaked in a solution of 20% chloral hydrate and then mounted on a glass slide with the help of glycerine. The mounted slides were then observed under a photographic microscope. Microscopic sections were cut by free hand sectioning.

Result: The research paper study revealed that the yellow colour inside the rhizome is the main characteristic feature. The presence of central cylinder region containing yellow coloured oleo-resin and oil cells in cortex are the main characteristic feature. The presence irregularly rounded, ovoid starch grains and oil globulues situtated inside the parenchyma are the distinguishing features and can be used as anatomical markers. Rhizome powder showed some of the characteristic features such as starch grains with a rounded shape situated at narrow end and parenchymatous cells with characteristically wrinkled wall, air spaces. Cork, cortex, cork cells, and floem fibres also shows pharmacognostical characteristics of Z. cassumunar Roxb. Preliminary phytochemical analysis of the rhizomes revealed the presence of glycosides, sterols, triterpenes, saponins, tannins, flavonoids, amino acids and volatile oils.

Conclusion:The present study signifies the use of TLC (Thin layer chromatography) profiles for determining the identity of active chemical constituents.

Keywords: Zingiber cassumunar Roxb, Indigenous medicines, Oil globulues, Pharmacognostical characteristics, Thin layer chromatographic.

Author Biography

Akshada Amit Koparde, Department of Pharmaceutical Chemistry, Rajarambapu College of Pharmacy, Kasegaon, Sangli, Maharashtra, India.
Department of pharmaceutical Chemistry

References

1. Mukherjee P. Quality Control of Herbal Drugs – An Approach to Evaluations of Botanicals. 5th ed. New Delhi: Business Horizons; 2005. p. 2.
2. Vogel GH. Drug Discovery and Evaluation: Pharmacological Assays. Cham: Springer; 2003. p. 202.
3. Pongprayoon U, Soontornsaratune P, Jarikasem S, Sematong T, Wasuwat S, Claeson P. Topical antiinflammatory activity of the major lipophilic constituents of the rhizome of Zingiber cassumunar. Part I: The essential oil. Phytomedicine 1997;3:319-22.
4. Tewtrakul S, Subhadhirasakul S. Anti-allergic activity of some selected plants in the Zingiberaceae family. J Ethnopharmacol 2007;109:535-8.
5. Lu Y, Sun C, Wang Y, Pan Y. Preparative isolation and purification of two phenylbutenoids from the rhizomes of Zingiber cassumunar by upright counter-current chromatography. J Chromatogr A 2005;1089(1-2):258-62.
6. Khandelwal KR. Practical Pharmacognosy. 16th ed. Pune: Nirali Publication; 2010. p. 149-61.
7. Ahmed RS, Sharma SB. Biochemical studies on combined effects of garlic (Allium sativum Linn) and ginger (Zingiber officinale Rosc) in albino rats. Indian J Exp Biol 1997;35:841-3.
8. Grzanna R, Lindmark L, Frondoza CG. Ginger – An herbal medicinal product with broad anti-inflammatory actions. J Med Food 2005;8:125-32.
9. Prakash RO, Kumar RK, Rabinarayan A, Kumar MS. Pharmacognostical and phytochemical studies of Zingiber Zerumbet (L.) Sm. Rhizome. Int J Res Ayurveda Pharm 2011;2(3):698-703.
10. Varier PS. Indian Medicinal Plants – A Compendium of 500 Species. Vol. 1. Kottakkal-India: Orient Longman Publishing House; 2002. p. 146.
11. Nancy P, Ashlesha V. Pharmacognostic and phytochemical studies of cassia absus seed extracts. Int J Pharm Pharm Sci 2016;8(1):325-32.
12. Government of India. The Ayurvedic Pharmacopoeia of India. 1st ed. New Delhi: Ministry of Health and Family Welfare, Department of Indian Systems of Medicines and Homeopathy; 2009. p. 242-4.
13. Kokate CK. Practical Pharmacognosy. 4th ed. New Delhi: Vallabh Prakashan; 2010. p. 17-26.
14. Kokoski CJ, Kokoski RJ, Slama FJ. Fluorescence of powdered vegetable drugs under ultraviolet radiation. J Am Pharm Assoc Am Pharm Assoc 1958;47:715-7.
15. WHO. Quality Control Methods for Medicinal Plant Material. Geneva: WHO; 1992. p. 22-34.
16. Government of India. Indian Pharmacopeia. 4th ed. New Delhi: Ministry of Health and Welfare, Controller of Publications; 2007. p. A53-4.
17. Koparde AA, Magdum CS. Conventional and microwave assisted extraction of Eulophia ochreta Lindl and Zingiber cassumunar Roxb: An comparitive account. Res J Pharm Tech 2014;7(7):746-8.
18. Khadabadi SS, Deore SL, Baviskar BA. Experimental Phytopharmacognosy: A Comprehensive Guide. 1st ed., Annx-2. India: Nirali Prakashan; 2011. A2.1.
19. Kumar S, Kumar V, Prakash OM. Pharmacognostic study and anti-inflammatory activity of Callistemon lanceolatus leaf. Asian Pac J Trop Biomed 2011;1:177-81.
20. Jain S, Koka S, Gupta A, Barik R, Malviya N. Standardization of “Chopchiniyadi Churna”: An ayurvedic polyherbal formulation. Phcog J 2010;2(5):60-4.
21. Kumar D, Gupta J, Kumar S, Arya R, Kumar T, Gupta A. Pharmacognostic evaluation of Cayratia trifolia (Linn.) leaf. Asian Pac J Trop Biomed 2012;2:6-10.
22. Netala S, Penmetsa R, Nakka S, Polisetty BL. Pharmacognostic study of Callistemon Citrinus L. bark. Int J Pharm Pharm Sci 2015;7(1):427-30.
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Koparde, A. A., and M. Cs. “PHYTOCHEMICAL STUDIES AND PHARMACOGNOSTICAL EVALUATION OF ZINGIBER CASSUMUNAR ROXB”. Asian Journal of Pharmaceutical and Clinical Research, Vol. 10, no. 10, Sept. 2017, pp. 129-35, doi:10.22159/ajpcr.2017.v10i10.20004.
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