INVESTIGATION OF ANTIOXIDANT POTENTIAL OF QUERCETIN AND HESPERIDIN: AN IN VITRO APPROACH


Srimathi Priyanga K, Vijayalakshmi K

Abstract


 

 Objective: The study was carried out to evaluate the antioxidant potential of quercetin and hesperidin.

Methods: The antioxidant potential of quercetin and hesperidin was estimated using free radicals in in vitro condition. Antioxidant activity of quercetin and hesperidin was estimated using 1,1-diphenyl-2-picrylhydrazyl (DPPH), superoxide, nitric oxide, hydroxyl radical, hydrogen peroxide radical, and reducing power assay.

Results: Quercetin and hesperidin have high efficiency in scavenging free radicals. Both the compounds are more efficient in scavenging DPPH (IC50 value 36.15±0.30 and 41.55±0.49 mg/ml) and superoxide radicals (IC 50 value 19.3±0.26 and 28.08 ±0.18 mg/ml) have high reducing capacity when compared to the standards ascorbic acid (IC50 value 31.45±1.31 and 23.2±0.20 mg/ml).

Conclusion: The present study suggests that quercetin and hesperidin have significant antioxidant activities and could be easily accessible to the immune system.


Keywords


Quercetin, Hesperidin, 1,1-diphenyl-2-picrylhydrazyl, Radical scavenging activity.

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About this article

Title

INVESTIGATION OF ANTIOXIDANT POTENTIAL OF QUERCETIN AND HESPERIDIN: AN IN VITRO APPROACH

Keywords

Quercetin, Hesperidin, 1,1-diphenyl-2-picrylhydrazyl, Radical scavenging activity.

DOI

10.22159/ajpcr.2017.v10i11.20260

Date

01-11-2017

Additional Links

Manuscript Submission

Journal

Asian Journal of Pharmaceutical and Clinical Research
Vol 10 Issue 11 November 2017 Page: 83-86

Print ISSN

0974-2441

Online ISSN

2455-3891

Statistics

19 Views | 61 Downloads

Authors & Affiliations

Srimathi Priyanga K
Department of Biochemistry, Bharathi Women’s College, Chennai - 600 108, Tamil Nadu, India
India

Vijayalakshmi K
Department of Biochemistry, Bharathi Women’s College, Chennai - 600 108, Tamil Nadu, India
India


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