EVALUATION OF ANTIMICROBIAL AND SYNERGISTIC ANTIMICROBIAL PROPERTIES OF PTEROCARPUS SANTALINUS


Savan Donga, Pooja Moteriya, Sumitra Chanda

Abstract


Objectives: The aim of the present study was to evaluate antibacterial and synergistic antimicrobial properties of leaf, stem and bark of Pterocarpus santalinus. Methods: The extraction was done by decoction method. The antimicrobial activity was done by agar well diffusion assay and the synergistic antimicrobial activity was done by agar disc diffusion assay.  Results: The synergistic activity was studied with plant extracts plus antibiotics viz. Ampicillin , Polymyxin-B,  Clotrimazole and  Fluconazole.  Conclusions: Amongst the three parts, the best antimicrobial activity was shown by bark extract. All the three parts showed synergistic antimicrobial activity with antibiotics but their level varied.  The results suggest that all the three parts phytochemicals that enhance the antimicrobial efficacy of the antibiotics against some microorganisms and hence can be developed as a new therapeutic weapon against infectious diseases.


Keywords


Pterocarpus santalinus, Synergistic antimicrobial activity, Antibiotics, Bark, Fluconazole.

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References


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About this article

Title

EVALUATION OF ANTIMICROBIAL AND SYNERGISTIC ANTIMICROBIAL PROPERTIES OF PTEROCARPUS SANTALINUS

Keywords

Pterocarpus santalinus, Synergistic antimicrobial activity, Antibiotics, Bark, Fluconazole.

DOI

10.22159/ajpcr.2017.v10i11.20939

Date

01-11-2017

Additional Links

Manuscript Submission

Journal

Asian Journal of Pharmaceutical and Clinical Research
Vol 10 Issue 11 November 2017 Page: 204-209

Print ISSN

0974-2441

Online ISSN

2455-3891

Statistics

17 Views | 69 Downloads

Authors & Affiliations

Savan Donga
Department of Biosciences, Phytochemical, Pharmacological and Microbiological Laboratory, Saurashtra University, Rajkot - 360 005, Gujarat, India
India

Pooja Moteriya
Department of Biosciences, Phytochemical, Pharmacological and Microbiological Laboratory, Saurashtra University, Rajkot - 360 005, Gujarat, India
India

Sumitra Chanda
Department of Biosciences, Phytochemical, Pharmacological and Microbiological Laboratory, Saurashtra University, Rajkot - 360 005, Gujarat, India
India


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