A STUDY ON ANTIMICROBIAL SENSITIVITY AND COST ANALYSIS OF ANTIBIOTICS IN PEDIATRIC UNIT AT A TERTIARY CARE HOSPITAL.


Alan Kurian, Aswini V, Shiva Ranjini B, Jerry Davis M, Rama P, Vadivel Vinoth

Abstract


 Objectives: (1) To determine the antimicrobial susceptibility pattern in pediatrics, (2) to identify the pattern of empirical antibiotic usage, (3) to determine the cost analysis of generic antibiotic usage pattern, (4) to assess the different dosage forms of antibiotics.

Methods: A retrospective observational study was carried out. The study population included the medical records of children aged day 1–15 years with bacterial infection who got admitted in the pediatric department of the hospital. The average cost for each generic dosage form of antibiotic was calculated.

Result: Among the 176 cases taken for the study, sepsis (35.8%) was found to be the most common disease. Bacterial infection showed gender predominance in males (62.5%) and occurrence of sepsis was highly found in age groups of 0–1 years (55.68%). Among the 14 causative organisms, methicillin-resistant coagulase negative staphylococci (61.93%) was predominant in Gram-positive and Escherichia coli (38.06%) for Gram-negative. Highly prescribed drug for empirical therapy was considered to be amikacin (39.20%). Widely prescribed antibiotics were amikacin (21%), ceftriaxone (15.1%), ampicillin (12.34%) and meropenem (9.57%), among which meropenem was found to be of high cost.

Conclusion: It should be taken care that the drug should be given not only based on the sensitivity pattern but can also consider the economic affordability of the patient, with reference to existing brands from the formulary. This would help in reducing the burden of health-care cost for the patients.


Keywords


Antimicrobial agents, Blood stream infection, Neonatal intensive care unit, Medical records department, Hospital information system.

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About this article

Title

A STUDY ON ANTIMICROBIAL SENSITIVITY AND COST ANALYSIS OF ANTIBIOTICS IN PEDIATRIC UNIT AT A TERTIARY CARE HOSPITAL.

Topics

Pharmacy Practice

Keywords

Antimicrobial agents, Blood stream infection, Neonatal intensive care unit, Medical records department, Hospital information system.

DOI

10.22159/ajpcr.2018.v11i2.21075

Date

01-02-2018

Additional Links

Manuscript Submission

Journal

Asian Journal of Pharmaceutical and Clinical Research
Vol 11 Issue 2 February 2018 Page: 242-251

Print ISSN

0974-2441

Online ISSN

2455-3891

Authors & Affiliations

Alan Kurian
Department of Pharmacy Practice, PSG College of Pharmacy, Coimbatore, Tamil Nadu India.
India

Aswini V
Department of Pharmacy Practice, PSG College of Pharmacy, Coimbatore, Tamil Nadu India.
India

Shiva Ranjini B
Department of Pharmacy Practice, PSG College of Pharmacy, Coimbatore, Tamil Nadu India.
India

Jerry Davis M
Department of Pharmacy Practice, PSG College of Pharmacy, Coimbatore, Tamil Nadu India.
India

Rama P
Department of Pharmacy Practice, PSG College of Pharmacy, Coimbatore, Tamil Nadu India.
India

Vadivel Vinoth
Department of Pharmacy Practice, PSG College of Pharmacy, Coimbatore, Tamil Nadu India.
India


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