EVALUATION OF AQUEOUS AND ETHANOLIC EXTRACTS OF SYZYGIUM CARYOPHYLLATUM FOR ANTIBACTERIAL ACTIVITIES


Raghunath Pendru, Jagan Nadipelly, Jyothinath Kothapalli, Subbannayya Kotigadde

Abstract


 Objective: It has been well documented that traditional medicinal plants confer considerable antimicrobial activity against various microorganisms.

Methods: The present study was designed to evaluate the antimicrobial properties of aqueous and ethanolic extracts of the leaves of Syzygium caryophyllatum against Staphylococcus aureus, Escherichia coli, Salmonella typhi, Shigella flexneri, and Vibrio cholerae. The aqueous extract was prepared using cold percolation method, and ethanolic extract was prepared in Soxhlet apparatus using ethyl alcohol. Antimicrobial activity is being determined by time-kill assay and minimum inhibitory concentration.

Results: From our study, it is found that all tested organisms were sensitive to both aqueous and ethanolic extract of leaves of S. caryophyllatum. The ethanolic extract showed better antibacterial activity against S. aureus and S. typhi when compare to aqueous extract. The phytochemical analysis confirmed the presence of flavonoids, alkaloids, glycosides, steroids, phenols, tannins, and saponins in the ethanolic and aqueous extract of S. caryophyllatum.

Conclusion: We hypothesize that these active phytoconstitutents might be responsible for the antimicrobial activity of this plant.


Keywords


Syzygium caryophyllatum, Antimicrobial property, Time-kill assay, Minimum inhibitory concentration.

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References


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About this article

Title

EVALUATION OF AQUEOUS AND ETHANOLIC EXTRACTS OF SYZYGIUM CARYOPHYLLATUM FOR ANTIBACTERIAL ACTIVITIES

Topics

Pharmacology

Keywords

Syzygium caryophyllatum, Antimicrobial property, Time-kill assay, Minimum inhibitory concentration.

DOI

10.22159/ajpcr.2018.v11i2.21687

Date

01-02-2018

Additional Links

Manuscript Submission

Journal

Asian Journal of Pharmaceutical and Clinical Research
Vol 11 Issue 2 February 2018 Page: 235-237

Print ISSN

0974-2441

Online ISSN

2455-3891

Statistics

20 Views | 30 Downloads

Authors & Affiliations

Raghunath Pendru
Department of Microbiology, School of Medicine, Texila American University, Guyana, South America.
Guyana

Jagan Nadipelly
Department of Pharmacology,School of Medicine, Texila American University, Guyana, South America.
Guyana

Jyothinath Kothapalli
Department of Anatomy, Maheshwara Medical College and Hospital, Chitkul, Isnapur, Patancheru, Telangana.
India

Subbannayya Kotigadde
Department of Microbiology, K.V.G Medical College and Hospital, Sullia, Karnataka.
India


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