STUDY OF GLYCATED HEMOGLOBIN LEVELS IN POLYCYSTIC OVARY SYNDROME

Authors

  • Renuka P Department of Biochemistry, SRM Medical College Hospital & Research Centre, Kattankulathur, Kancheepuram - 603 203, Tamil Nadu,India.
  • Shakthiya T Department of Biochemistry, SRM Medical College Hospital & Research Centre, Kattankulathur, Kancheepuram - 603 203, Tamil Nadu,India.
  • Vinodhini Vm Department of Biochemistry, SRM Medical College Hospital & Research Centre, Kattankulathur, Kancheepuram - 603 203, Tamil Nadu,India.

DOI:

https://doi.org/10.22159/ajpcr.2018.v11i5.22729

Keywords:

Glycated hemoglobin, Polycystic ovarian syndrome, Pre-diabetes, Type 2 diabetes mellitus

Abstract

 Objective: Polycystic ovarian syndrome (PCOS) is often accompanied by insulin resistance, obesity, and cardiometabolic risk factors. Androgen excess-PCOS recommends oral glucose tolerance test or glycated hemoglobin (HbA1C) to evaluate dysglycemia in PCOS subjects. We undertook this study to evaluate the prevalence of elevated HbA1C levels in PCOS women.

Methods: The study was carried out among 100 PCOS patients from SRM Hospital, 100 healthy individuals were included as controls. Fasting glucose, HbA1C, Insulin and Homeostasis Model Assessment-Insulin Resistance Index were estimated.

Results: Patients with polycystic ovary syndrome showed a significant increase in HbA1C levels (5.799±1.022; 4.96±0.625, p=0.001) when compared to the control group.

Conclusion: We found elevated HbA1C levels in PCOS women categorizing 26% as prediabetes and 28% as having type 2 diabetes mellitus.

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Author Biographies

Renuka P, Department of Biochemistry, SRM Medical College Hospital & Research Centre, Kattankulathur, Kancheepuram - 603 203, Tamil Nadu,India.

Dr.Renuka

Professor

Department of Biochemistry

SRM Medical College Hospital & Research Center

E-mail: rpangaluri@gmail.com

Shakthiya T, Department of Biochemistry, SRM Medical College Hospital & Research Centre, Kattankulathur, Kancheepuram - 603 203, Tamil Nadu,India.

M.Sc student, Department of Biochemistry

Vinodhini Vm, Department of Biochemistry, SRM Medical College Hospital & Research Centre, Kattankulathur, Kancheepuram - 603 203, Tamil Nadu,India.

Professor & Head

Department of Biochemistry

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Published

01-05-2018

How to Cite

P, R., S. T, and V. Vm. “STUDY OF GLYCATED HEMOGLOBIN LEVELS IN POLYCYSTIC OVARY SYNDROME”. Asian Journal of Pharmaceutical and Clinical Research, vol. 11, no. 5, May 2018, pp. 191-3, doi:10.22159/ajpcr.2018.v11i5.22729.

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Original Article(s)