• VASUNDRA DEVI P.A Bharathiar UniversityCoimbatoreTamilnadu



Objective: To evaluate and compare the in vivo antipyretic activity of the aqueous and the ethanol extract of root of Asparagus racemosus. Methods: The presence of phytochemicals like flavonoids and saponins were identified by TLC and the invivo antipyretic activity was determined by brewer's yeast induced pyrexia method. Results: The results showed that the ethanol extract of root of Asparagus racemosus possessed significant antipyretic effect compared to the aqueous extract which may be attributed to the presence of flavonoids and saponins in the extracts whose presence were observed in TLC. Conclusion: This study provides evidences for the antipyretic activity of Asparagus racemosus which could partly contribute to its ethno medical use.


Key Words: Asparagus racemosus, Antipyretic effect, flavonoids ,saponins, TLC

Author Biography

VASUNDRA DEVI P.A , Bharathiar UniversityCoimbatoreTamilnadu

Assistant ProfessorDept of BiochemistryDr.N.G.P Arts and Science CollegeCoimbatore - 641048



Hazeena Begum V and Velavan S. Lipids regulating activity of Asparagus racemosus root in young and aged rats. Indian Journal of Gerontology, 2011, 25(3): 273-285.

Ignacimuthu. S. and Ayyanar M. Herbal medicines for wound healing among tribal people

in Southern India: Ethno botanical and Scientific evidences. International Journal of Applied Research in Natural Products, 2009, 2 (3): 29-42.

Rajani G. P., Deepak Gupta, Sowjanya K, and Sahithi B. Screening of antipyretic activity of aerial parts of Nelumbo nucifera gaertn in yeast induced pyrexia . Pharmacologyonline, 2011 1: 1120-1124.4. Duraisankar M. and Ravichandran V. Antipyretic Potential of Polyherbal Ayurvedic Products. Asian Journal Pharmaceutical and Clinical Research, 2012, 5 (2), 146 – 150.

Gupta M., B.P. Shaw and A. Mukerjee. Studies on Antipyretic Analgesic and Ulcerogenic

Activity of Polyherbal Preparation in Rats and Mice. Intl.Journal of Pharmacology, 2008, 4(2): 88-94.

Ighodaro Igbe, Raymond I Ozolua, Steve O Okpo and Osahon Obasuyi. Antipyretic and

analgesic effects of the aqueous extract of the Fruit pulp of Hunteria umbellata K Schum

(Apocynaceae) . Tropical Journal of Pharmaceutical Research, 2009, 8(4): 331-336.

Periyasamy Gomathi, Upal Kanti Mazumder and Malaya Gupta. Antipyretic potential of

Galega pupurea root, .Intl. Research Journal of Pharmacy, 2011, 2(11): 151-152.

Michael Thomsen. Herbal Monograph-Asparagus racemosus, Phytomedicine, 2002, 1-4.

Fasalu Rahiman O.M, Bodapati Srilatha, Rupesh Kumar M, Mohamed Niyas K, Satya

Kumar B, and Phaneendra P. Analgesic activity of aqueous and alcohol root extract of

Asparagus racemosus Willd . Pharmacologyonline, 2011, 2: 558-562.

Ashajyothi V., Dr. Rao Pippalla and Dr. D. Satyavati. Asparagus racemosus- Phytoestrogen Int. Journal Of Pharmacy& Technology, 2009, 1: 36-47.

Arun Vijayan, Liju V.B., Reena John, Parthipan B. and Renuka C. Traditional remedies of

Kani tribes of Kottoor reserve forest, Agasthayavanam,Thiruvananthapuram, Kerala. Indian

Journal of Traditional Knowledge, 2007, 6(4): 589-594.

Bhaskar V.H. and Balakrishnan N. Analgesic, anti-inflammatory and antipyretic activities of

Pergularia daemia and Carissa carandas. DARU, 2009, 17(3): 168-17.

Amiya R. Padhan, Anuj Kumar Agrahari and Ashutosh Meher. A study on antipyretic

activity of Capparis zeylanica linn. plant methanolic extract.International Journal of Pharma

Sciences and Research (IJPSR), 2010, 1(3):169-171.

Goel RK, Prabha T, Kumar MM, Dorababu M. Teratogenicity of Asparagus racemosus

willd. root, a herbal medicine.Indian J Exp Biol,2006.44 (July): 570-573.

Junaid Niazi, Vikas Gupta, Prithviraj Chakarborty and Pawan Kumar. Anti-inflammatory

and antipyretic activity of Aleuritis moluccana leaves .Asian Journal of Pharmaceutical

and Clinical Research, 2010, 3(1): 35-37.

Fried B. and Sherma J. Thin-layer chromatography: techniques and applications. Third

edition,Chromatographic science series 66. Marcel Dekker,New York,USA,1994.451.

Potduang Buppachart, Maneerat Meeploy, Rattanasiri Giwanon, Yaowaluck Benmart,

Montree Kaewduang, and Winai Supatanakul. Biological Activities of Asparagus

racemosus . Afr J Tradit Complement Altern Med. 2008, 5(3): 230–237.

Warner Timothy and Mitchell Jane A. Cyclooxygenase-3 (COX-3): Filling in the gaps

toward a COX continuum Proc. Natl. Acad. Sci. USA, 2002, (99):13926–13931.

Mahesh S. Paschapur, Swati Patil, Sachin R. Patil, Ravi Kumar and M. B. Patil.

Evaluation of the analgesic and antipyretic activities of ethanolic extract of male

flowers (inflorescences) of Borassus flabellifer (arecaceae).Intl. Journal of Pharmacy

and Pharm. Research.,1(2): 99-106.

Nagaveni.P, Saravana Kumar.K, andGrace Rathnam. Phytochemical Profile and

Antipyretic Activity of Mangifera Indica . JITPS, 2011, 6:167-173.

Sankar Anand, Subhadra Devi, Arunprasath B., Subageetha A.and C. H. Anusha. Boiled

milk induced pyrexia in rabbits- antipyretic activity Vernonia cinerea roots . IJPSR,

, 2(1): 127-131.

Aman A. Alzubier and Patrick N.Okechukwu, Investigation of anti-inflammatory,

antipyretic and analgesic effect of Yemeni Sid honey, World Academy of Science,

Engineering and Technology, 2011, 80:47-52.

Jude E Okokon and Paul Nwafor. Antiinflammatory, analgesic and antipyretic activities

of ethanol root extract of Croton zambesicus .Pak. J. Pharm. Sci.2010, 23(4): 385-392.

Adesokan A.A, Yakubu M.T.,Owoyele B.V., Akanji M.A., Soladoye A.O. and LawalO.

Effect of administration of aqueous and ethanol extracts of Enantia chlorantha stem bark

on brewer’s yeast induced pyresis in rats. African J of Biochemistry,2008, 2(7): 165-169.

Germain S.Taiwe, Elisabeth Ngo Bum, Theophile Dimo, Emmanuel Talla, Norbert

Weiss Neteydji Sidiki, Amadou Dawe, Fleur Clarisse Okomolo Moto, Paul Desire and

MichelWaard.Antipyretic and antinociceptive effects of Nauclea latifolia roots decoction

and possible mechanisms of action .Pharm Biol.,2011, 49(1):15-25.

Zakaria Z, Loo Yi Wen, Nurul Izzah Abdul Rahman, Abdul Halim Abdul Ayub, Mohd.

Roslan Sulaiman and Hanan Kumar Gopalan. Antinociceptive, Anti-Inflammatory and

Antipyretic properties of the aqueous extract of Bauhinia purpurea leaves in experimental

animals .Medical Principles and Practice, 2007, 16:443-449



How to Cite

P.A , V. D., and D. P. s. “ANTIPYRETIC ACTIVITY OF ETHANOL AND AQUEOUS EXTRACT OF ROOT OF ASPARAGUS RACEMOSUS IN YEAST INDUCED PYREXIA”. Asian Journal of Pharmaceutical and Clinical Research, vol. 6, no. 7, Aug. 2013, pp. 190-3,