ANTIBACTERIAL EFFECT OF JAVA TURMERIC ETHANOL EXTRACT AGAINST DUAL-SPECIES STREPTOCOCCUS MUTANS AND STREPTOCOCCUS SANGUINIS BIOFILM (IN VITRO)


Ajrina Busri, Ria Puspitawati, Sri Utami

Abstract


Objectives: The minimal bactericidal concentration (MBC) of Java turmeric (Curcuma xanthorrhiza Roxb.) ethanol extract is 25% against Streptococcus mutans and 15% against Streptococcus sanguinis as single species. This study aimed to examine the antibacterial effect of Java turmeric ethanol extract against S. mutans and S. sanguinis as dual-species. S. mutans and S. sanguinis compete against each other to obtain nutrients.

Methods: The antibacterial effect of Java turmeric ethanol extract against dual-species Streptococcus in vitro was analyzed by measuring the growth of bacteria after exposure to the extract by counting colony formation and quantifying bacterial cell numbers using real-time polymerase chain reaction.

Result: The MBC of Java turmeric ethanol extract against dual-species Streptococcus is 10%. S. sanguinis is more sensitive to the extract than S. mutans.

Conclusions: The antibacterial effect of Java turmeric ethanol extract on S. mutans and S. sanguinis as single species differs from the effect on the bacteria as dual-species of Streptococcus.


Keywords


Dual-species Streptococcus, Java turmeric ethanol extract, Streptococcus mutans, Streptococcus sanguinis.

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About this article

Title

ANTIBACTERIAL EFFECT OF JAVA TURMERIC ETHANOL EXTRACT AGAINST DUAL-SPECIES STREPTOCOCCUS MUTANS AND STREPTOCOCCUS SANGUINIS BIOFILM (IN VITRO)

Keywords

Dual-species Streptococcus, Java turmeric ethanol extract, Streptococcus mutans, Streptococcus sanguinis.

DOI

10.22159/ajpcr.2017.v10s5.23096

Date

01-10-2017

Additional Links

Manuscript Submission

Journal

Asian Journal of Pharmaceutical and Clinical Research
Vol. 10, Special Issue (Oct.), 2017 [PTMDS 2017] Page: 57-60

Print ISSN

0974-2441

Online ISSN

2455-3891

Statistics

104 Views | 55 Downloads

Authors & Affiliations

Ajrina Busri
Department of Oral Biology, Faculty of Dentistry, Universitas Indonesia, Jakarta, Indonesia
Indonesia

Ria Puspitawati
Department of Oral Biology, Faculty of Dentistry, Universitas Indonesia, Jakarta, Indonesia
Indonesia

Sri Utami
Department of Oral Biology, Faculty of Dentistry, Universitas Indonesia, Jakarta, Indonesia
Indonesia


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