IN VITRO DETERMINATION OF SUN PROTECTION FACTORS ON ETHANOL EXTRACT AND NANOSTRUCTURED LIPID CARRIER-BASED GEL EXTRACT OF MULBERRY ROOT (MORUS ALBA L.)

Authors

  • Faizatun Faizatun Department of Pharmaceutical Technology, Faculty of Pharmacy, University of Pancasila, Jakarta, Indonesia.
  • Shella Dayu Asto Department of Pharmaceutical Technology, Faculty of Pharmacy, University of Pancasila, Jakarta, Indonesia.

DOI:

https://doi.org/10.22159/ajpcr.2018.v11s1.26590

Keywords:

Mulberry root extract, Sun protective factor, Nanostructured lipid carrier, Spectrophotometry

Abstract

Objective: The purpose of this study was to determine the potential of sun protection factors on extract and nanostructured lipid carrier (NLC) gel of mulberry root extract.

Methods: In this study, the root mulberry (Morus alba L.) was extracted using 96% ethanol and tested its sun protective factor (SPF) values. Mulberry root extract made into NLC with solvent evaporation method. The NLC was evaluated and dispersed into the gel, NLC gel was tested SPF value by petro method.

Results: The result shows that the SPF value extracts of mulberry root at the concentration 300 ppm, 400 ppm, and 500 ppm were 10.84, 28.17, and 66.65, respectively. While the SPF values of NLC gel extract of mulberry root at the concentration of 300 ppm, 400 ppm, and 500 ppm were 9.11, 22.87, and 45.76, respectively.

Conclusion: It could be concluded that extract and NLC gel of mulberry root extract have potential in ultraviolet protection against the skin.

References

Saraf S, Kaur CD. Phytoconstituents as Photoprotective Novel Cosmetic Formulations. 2010;47:1-11. Available from: https://www. researchgate.net/publication/215908316.

Bonina F, Lanza M, Montenegro L, Puglisi C, Tomaino A. Flavonoid as potensial protective agent photooxidative skin damage. Int J Pharm 1996;145:87-94.

Soares LL, Bassani VL, Ortega G, Petrovick PR. Total flavonoid determination for the quality control of aqueous extractives from Phyllanthus niruri L. Lat. Am J Pharm 2003;22:203-7.

Petro AJ. Correlation of spectrophotometric data with sunscreen protection factors. Int J Cosmetic Sci 1981;3;185-96.

Gao Z, Huang K, Xu H. Protective effects of flavonoids in the roots of Scutellaria baicalensis Georgii against hydrogen peroxideinduced oxidative stress in HS-SY5Y cells. Pharmacol Res 2001;43:173-8.

Imam S, Azhar I, Mahmood ZA. In-vitro evaluation of sun protection factor of a cream formulation prepared from extracts of Musa Accuminata (l.), Psidium Gujava (l.) and Pyrus Communis (l.). Asian J Pharm Clin Res 2015;8:234-7.

Morganti P. Use and potential of nanotechnology in cosmetic dermatology. Clin Cosmet Investig Dermatol 2010;3:5-13.

Dutra EA, Oliveira DA, Kedor-Hackman MI. Determination of sun protection factor (SPF) of sunscreens by ultraviolet spectrophotometry. Braz J Pharm Sci 2004;40:381-7.

Purwaningsih S, Salamah E, Adnin MN. Effect of photoprotective sunscreen cream with addition of gifts and black mangrove fruit (Rhizopora mucronata L.). J Trop Mar Sci Technol 2015;7:1-14.

Published

2018-04-26

How to Cite

Faizatun, F., and S. D. Asto. “IN VITRO DETERMINATION OF SUN PROTECTION FACTORS ON ETHANOL EXTRACT AND NANOSTRUCTURED LIPID CARRIER-BASED GEL EXTRACT OF MULBERRY ROOT (MORUS ALBA L.)”. Asian Journal of Pharmaceutical and Clinical Research, vol. 11, no. 13, Apr. 2018, pp. 138-40, doi:10.22159/ajpcr.2018.v11s1.26590.

Issue

Section

Original Article(s)