MICRO RAMAN SPECTROSCOPIC ANALYSIS ON BLOOD SERUM SAMPLES OF DUCTAL CARCINOMA PATIENTS

Sanoj Varghese; Ambili Reveendran; V.senthil Kumar; Karthikeyan Tm; Venkiteshan Ranganathan

doi:10.22159/ajpcr.2018.v11i9.26806

Authors

Sanoj Varghese Department of Physics, Karpagam Academy of Higher Education, Coimbatore â€“ 641 021, Tamil Nadu, India.
Ambili Reveendran Department of Physics, Karpagam Academy of Higher Education, Coimbatore â€“ 641 021, Tamil Nadu, India.
V.senthil Kumar Department of Physics, Karpagam Academy of Higher Education, Coimbatore â€“ 641 021, Tamil Nadu, India.
Karthikeyan Tm Department of Pathology, Karpagam Faculty of Medical Sciences and Research, Coimbatore â€“ 641 032, Tamil Nadu, India.
Venkiteshan Ranganathan Department of Oncology, Karpagam Faculty of Medical Sciences and Research, Coimbatore â€“ 641 032, Tamil Nadu, India.

DOI:

https://doi.org/10.22159/ajpcr.2018.v11i9.26806

Keywords:

Ductal cancer, Spectroscopy, Blood serum, Scattering

Abstract

Objective: Identification of biochemical changes in ductal cancer patient's serum samples using micro Raman spectroscopy.

Methods: Micro Raman spectroscopy was used for the identification of Raman shift bands. Data analysis was done using K-means clustering.

Results: Micro Raman spectroscopic analysis of human breast cancer patient's serum samples was done. Biochemicals present in the samples were identified from the peak evaluations. K-means clustering analysis was used to differentiate the biochemicals present in the samples.

Conclusion: From the study, we conclude that Raman spectroscopy has the potential to differentiate the biochemical changes occurring in the human body, and the differentiation can be done using K-means clustering.

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Author Biographies

Sanoj Varghese, Department of Physics, Karpagam Academy of Higher Education, Coimbatore â€“ 641 021, Tamil Nadu, India.

Research Scholar, Department of Physics, Karpagam Academy of Higher Education

Ambili Reveendran, Department of Physics, Karpagam Academy of Higher Education, Coimbatore â€“ 641 021, Tamil Nadu, India.

Research Scholar, Department of Physics

V.senthil Kumar, Department of Physics, Karpagam Academy of Higher Education, Coimbatore â€“ 641 021, Tamil Nadu, India.

Professor and Head, Department of Physics

Karthikeyan Tm, Department of Pathology, Karpagam Faculty of Medical Sciences and Research, Coimbatore â€“ 641 032, Tamil Nadu, India.

Professor and Head, Department of Pathology

Venkiteshan Ranganathan, Department of Oncology, Karpagam Faculty of Medical Sciences and Research, Coimbatore â€“ 641 032, Tamil Nadu, India.

Assistant professor, Depart of Oncology

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