STUDY ON MULTIPOTENT MEDICINAL ASPECTS OF SCHIMA WALLICHII (BARK) FROM NAGALAND, NE INDIA

  • MINAKSHI BHATTACHARJEE Department of Biotechnology, Assam Down Town University, Guwahati, Assam, India.
  • VITOLU SEMA Y Department of Biotechnology, Assam Down Town University, Guwahati, Assam, India.
  • MANASH PRATIMSARMA Department of Biotechnology, Assam Down Town University, Guwahati, Assam, India.

Abstract

Objective: The present study focuses on the multipotent medicinal aspects of Schima wallichii bark.


Methods: The ethanol and water extracts of the plant were investigated its phytochemical, antibacterial, antioxidant, and anticoagulant as per the standard method.


Results: S. wallichii bark extract was effective against Staphylococcus aureus. It was also found to be a good antioxidant having an IC50 value of 98.7 in ethanolic extract. Further, the water extract increased in prothrombin time to 57.7 s against normal (12.3 s). The different phytochemicals, namely tannin, saponins, steroids, terpenoids, flavonoids, and glycosides, were present. Since the findings showed very less percent inhibition in comparison to curcumin-treated cells, thus both the extracts were both not effective in the antiproliferative assay.


Conclusion: We conclude that this plant is a good candidate for developing a natural drug.

Keywords: Schima wallichii, Antioxidants, 2,2-diphenyl-1-picrylhydrazylhydrate, Phytochemicals, Anticoagulase, Antimicrobial.

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BHATTACHARJEE, M., V. SEMA Y, and M. PRATIMSARMA. “STUDY ON MULTIPOTENT MEDICINAL ASPECTS OF SCHIMA WALLICHII (BARK) FROM NAGALAND, NE INDIA”. Asian Journal of Pharmaceutical and Clinical Research, Vol. 12, no. 3, Feb. 2019, pp. 155-8, https://innovareacademics.in/journals/index.php/ajpcr/article/view/29288.
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