EPIDEMIOLOGY, PATHOLOGY, TYPES AND DIAGNOSIS OF SOFT TISSUE SARCOMA: A RESEARCH REVIEW

  • RAJANYA BANERJEE Asst.Professor,School of biosciences and technology,VIT University, Vellore
  • DEBASMITA BANDOPADHYAY
  • V.G. ABILASH

Abstract

A sarcoma is a type of cancer disease which develops from certain tissues, like bone or muscle. The main types of sarcoma are: osteosarcoma and soft tissue sarcoma. Osteosarcoma which develops from bone and soft tissue sarcomas can develop from soft tissues like fat, muscle, nerves, fibrous tissues, blood vessels, or deep skin tissues. This article presents the overall information about the soft tissue sarcoma. Soft tissue sarcoma is an exceptional form of cancer which affects the adjoining body areas such as muscles, fat, fibrous tissue, blood vessels or else other supporting tissue of the body. Along with connective tissues many other parts of the body get mainly affected in this sarcoma, and when these parts get affected, they start dividing randomly and henceforth, create a lump. This lump exceeds in the shape due to internal pressure and causes a disruption in the neighboring organs of the body. It is a very rare cancer. About 1% among adult and 15% among the children is affected in this soft tissue sarcoma. Various types of genes are also present in inducing the soft tissue sarcomas are retinoblastoma protein 1(RB1); N-RAS; cyclic AMP dependent kinase number 2(CDKN2); protein 53 or tumor protein 53 (p53); Mouse double minute 2 homolog (MDM2). For detection mainly biopsy, CT scan or MRI is done and to pursue the treatment surgery, chemotherapy, radiation is given which may increase the survival rate of the patients.


 

Keywords: Soft tissue sarcoma, osteosarcoma, Cancer, Tissue, Muscle

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BANERJEE, R., D. BANDOPADHYAY, and V. ABILASH. “EPIDEMIOLOGY, PATHOLOGY, TYPES AND DIAGNOSIS OF SOFT TISSUE SARCOMA: A RESEARCH REVIEW”. Asian Journal of Pharmaceutical and Clinical Research, Vol. 6, no. 7, Aug. 2013, pp. 18-25, https://innovareacademics.in/journals/index.php/ajpcr/article/view/294.
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