Effects EFFECTS OF PUMPKIN (CUCURBITA MOSCHATA DURCH) SEED POWDER ON BLOOD GLUCOSE LEVEL IN STREPTOZOTOCIN-INDUCED MICE

  • NOVARIANTI MARBUN Faculty of Pharmacy, Helvetia Institute of Health, Medan, Indonesia.
  • RUTH MAYANA RUMANTI Faculty of Pharmacy, Helvetia Institute of Health, Medan, Indonesia.

Abstract

Objective: The aim of this research is to evaluate the antidiabetic effect of pumpkin seed powder in streptozotocin (STZ)-induced diabetic mice.


Methods: Pumpkin seed was used in seed powder suspension form and then evaluate the phytochemical screening and induced diabetic mice using STZ.


Results: The phytochemical screening showed that pumpkin seed powder has various of phytochemical compounds. The pumpkin seed powder (dose level 100, 150, and 200 mg/kg bw) showed a significant reduction of blood glucose.


Conclusions: Pumpkin seed powder significantly decreases blood glucose level in STZ-induced mice.

Keywords: Diabetes mellitus, Streptozotocin, Pumpkin, Powder, Seed, Mice

Author Biography

RUTH MAYANA RUMANTI, Faculty of Pharmacy, Helvetia Institute of Health, Medan, Indonesia.

Department of Pharmacy

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How to Cite
NOVARIANTI MARBUN, and RUTH MAYANA RUMANTI. “Effects EFFECTS OF PUMPKIN (CUCURBITA MOSCHATA DURCH) SEED POWDER ON BLOOD GLUCOSE LEVEL IN STREPTOZOTOCIN-INDUCED MICE”. Asian Journal of Pharmaceutical and Clinical Research, Vol. 12, no. 8, July 2019, pp. 274-6, https://innovareacademics.in/journals/index.php/ajpcr/article/view/33730.
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