PHYTOCHEMICAL INVESTIGATION OF TERMINALIA BELLIRICA FRUIT INSIDE

  • HAZRA K Department of Chemistry, Central Ayurveda Research Institute for Drug Development, Kolkata, West Bengal, India.

Abstract

Objective: The fruit of Terminalia bellirica Roxb. or Baheda (Family Combretaceae) is an extensively used herb in traditional medicines. The fruit as a whole or a part of it is used in traditional healing. Fruit has two major parts, namely, pericarp and seed, pericarp, in turn, consists of epicarp, mesocarp, and endocarp. Ayurvedic compound formulations such as Triphala and Pathyadi contain pericarp of the fruit. The present study is aiming a comparative phytochemical investigation of fruit parts such as epicarp, mesocarp, and seed along with the whole fruit.


Methods: The study included physicochemical evaluation, phytochemical screening, biochemical assay, and thin-layer chromatography profile of the inner parts of the fruit.


Results: The study shows that seeds are rich in essential oil (13.25%), but very poor quantity of phenolics (0.65 gallic acid equivalent [GAE]) and flavonoids (0.77 quercetin equivalent [QE]) is present compared to epicarp (139.05 GAE and 141.26 QE) and mesocarp (135.23 GAE and 142.05 QE). In addition to that, qualitative phytochemical screening revealed that seeds are void of steroids and lignans.


Conclusion: The study concluded that seeds are less important in respect to the presence of secondary metabolites. It may also be concluded that mesocarp and epicarp are holding major responsibilities of therapeutic values imposed on the fruit.

Keywords: Terminalia bellirica, Fruit parts, Phytochemicals, High-performance thin-layer chromatography

References

1. Narendra K, Khurana SM. Phytochemicals and medicinal potential of the Terminalia bellirica Roxb. (Bahera). Indian J Nat Prod Rad 2018;9:97-107.
2. Chopra RN, Nayar SL, Chopra IC. Glossary of Indian Medicinal Plants. 3rd ed. New Delhi: CSIR; 1992.
3. Swati K, Mythili KJ, Arun BJ, Shailendra G, Anant VB, Amit A, et al. A pharmacognostic, phytochemical and pharmacological review of Terminalia bellerica. J Pharmacogn Phytochem 2017;6:368-76.
4. Anonymous. Ayurvedic Formulary of India. 1st ed. New Delhi: Ministry of Health and Family Welfare, Government of India; 2001.
5. Gupta R, Singh RL, Dwivedi N. In vitro antioxidant activity and GC-MS analysis of the ethanolic extract of Terminalia bellerica Rxb. (Baheda). Int J Pharm Pharm Sci 2016;8:275-82.
6. Anrasorn S, Korkanok I. Immunomodulatory activity of an acetone extract of Terminalia bellerica Roxb fruit on the mouse immune response in vitro. Int J Pharm Pharm Sci 2014;6:274-8.
7. Deb A, Barua S, Das B. Pharmacological activities of Baheda (Terminalia bellerica): A review. J Pharmacogn Phytochem 2016;5:194-7.
8. Anonymous. Quality Control Methods for Herbal Materials. 1st ed. Geneva, Switzerland: World Health Organization; 2011. p. 45.
9. Harpreet S, Amrita M, Arun KM. Pharmacognostical and physicochemical analysis of Cleome viscosa L. seeds. Pharmacogn J 2017;9:372-7.
10. Tambe VD, Bhambar RS. Estimation of total phenol, tannin, alkaloid and flavonoid in Hibiscus tiliaceus Linn. wood extracts. Res Rev J Pharmacogn Phytochem 2014;2:41-7.
11. Milan SS. Total phenolic content, flavonoid concentration and antioxidant activity of Marrubium peregrinum L. Extracts. Kragujevac J Sci 2011;33:63-72.
12. Stahl E. Thin Layer Chromatography, A Laboratory Handbook. 1st ed. New Delhi: Springer (I) Pvt. Ltd.; 2005. p. 765.
Statistics
155 Views | 49 Downloads
How to Cite
HAZRA K. “PHYTOCHEMICAL INVESTIGATION OF TERMINALIA BELLIRICA FRUIT INSIDE”. Asian Journal of Pharmaceutical and Clinical Research, Vol. 12, no. 8, June 2019, pp. 191-4, https://innovareacademics.in/journals/index.php/ajpcr/article/view/34347.
Section
Original Article(s)