ANTIBACTERIAL ACTIVITY AND GAS CHROMATOGRAPHY–MASS SPECTROMETRY STUDIES OF ALGERIAN ATRIPLEX HALIMUS L.
Objective: The objective of the study was to find out the antibacterial efficacy and identify the main constituents of the essential oil of Atriplex halimus from southwest of Algeria.
Methods: The essential oil from the aerial parts of the endemic plant A. halimus (saltbush in English, qataf in Arabic) collected from the region of Sahara southwest of Algeria was isolated by hydrodistillation and analyzed by gas chromatography–mass spectrometry. Antibacterial potency of essential oil from this plant has been tested against Staphylococcus aureus (ATCC 29213), Escherichia coli (ATCC 25922), and Bacillus cereus (ATCC11778) by disk diffusion assay.
Results: The essential oil revealed the presence of 14 components, the dominant compounds arecadina-1(10), 4-diene (10.69%), germacrene D (9.79%), octane (9.37%), pelargonaldehyde (9.06%), 3-Furancarboxaldehyde (6.87%), β-pinene (2.6%), camphene (2.59%), and myrcene (2.10%). The essential oil exhibits very effective antimicrobial activity using disk diffusion assay method with minimum inhibitory concentration ranging from 0.82 μl/ml to 2.4525 μl/ml.
Conclusions: This result showed that this native plant may be a good candidate for further biological and pharmacological investigations.
2. Wong CH, Jager HJ. Salt-induced vesiculation in mesophyll cells of Atriplex species. Plant Sci Lett 1978;12:63-8.
3. Romera P, Fernández-Illescas F, Nieva FJ, Rodríguez-Rubio P, Sánchez-Gullón E, Muñoz-Rodríguez AF. Reproductive phenology and pre-dispersal fruit predation in Atriplex halimus L. (Chenopodiaceae). Bot Stud 2013;54:4.
4. Chikhi I, Allali H, Dib ME, Medjdoub H, Tabt B. Antidiabetic activity of aqueous leaf extract of Atriplex halimus L. (Chenopodiaceae) in streptozotocin-induced diabetic rats. Asian Pac J Trop Dis 2014;4:181-4.
5. Ort-90.ac J J, Mart90.ac J T C, Correal E, Simre B, Cenis JL. Genetic structure of Atriplex halimus populations in the Mediterranean Basin. Ann Bot 2005;95:827-34.
6. Abd El-Rahman HH, Mohamed MI, Gehad AE, Awadallah IM. Ameliorating the anti-nutritional factors effect in Atriplex halimus on sheep and goats by ensiling or polyethylene glycol supplementation. Int J Agric Biol 2006;8:766-9.
7. Nedjimia B, Daoud Y. Cadmium accumulationin Atriplex halimus subsp. schweinfurthii and its influence on growth, proline, root hydraulic conductivity and nutrient uptake. Flora 2009;204:316-24.
8. Kabbash A, Shoeib N. Chemical and biological investigation of some secondary metabolites in Atriplex halimus growing in Egypt. Nat Prod Commun 2012;7:1465-8.
9. Clauser M, Dall’Acqua S, Loi MC, Innocenti G. Phytochemical investigation on Atriplex halimus L. from Sardinia. Nat Prod Res 2013;27:1940-4.
10. Ozenda P. In: Flore Du Sahara. 2nd ed. Paris: CNRS; 1983.
11. Ziane L, Lazouni HA, Moussaoui A, Namidi N, Djellouli M, Belabbes A. Flavonoid from methanolic extract of Limoniastrum feei (girard) batt (Plumbaginaceae). Asian J Pharm Clin Res 2015;8:218-9.
12. Council of Europe. European Pharmacopoeia. 3rd ed. Strasbourg: Council of Europe; 1997.
13. Bajalana I, Pirbalouti AG. Variation in antibacterial activity and chemical compositions of essential oil from different populations of myrtle. Ind Crops Prod 2014;61:303-7.
14. Haiyan G, Lijuan H, Shaoyu L, Chen Z, Ashraf MA. Antimicrobial, antibiofilm and antitumor activities of essential oil of Agastache rugosa from Xinjiang, China. Saudi J Biol Sci 2016;23:524-30.
15. Boudjedjou L, Ramdani M, Zeraib A, Benmeddour T, Fercha A. Chemical composition and biological activities of Algerian Santolina africana essential oil. Sci Afr 2019;4:e00090.
16. Bajer T, Silha D, Ventura K, Bajerovi P. Composition and antimicrobial activity of the essential oil, distilled aromatic water and herbal infusion from Epilobium parviflorum Schreb. Ind Crops Prod 2017;100:95-105.
17. Raimundo KF, Bortolucci WC, Glamolucci J, Sokoviu M, Gonoviucc JE, Linde GA, et al. Antifungal activity of Gallesia integrifolia fruit essential oil. Braz J Microbiol 2018;49 Suppl 1:229-35.
18. Esmaeili H, Karami A, Maggi F. Essential oil composition, total phenolic and flavonoids contents, and antioxidant activity of Oliveria decumbens Vent. (Apiaceae) at different phenological stages. J Cleaner Prod 2018;198:91-5.
19. Sajjadi MH, Amiri H. Chemical constituents of the essential oils of different stages of the growth of Stachys lavandulifolia Vahl. from Iran. Pak J Biol Sci 2007;10:2784-6.
20. Djellouli M, Benmehdi H, Mammeri S, Moussaoui A, Ziane L, Hamidi N. Chemical constituents in the essential oil of the endemic plant Cotula cinerea (Del.) from the Southwest of Algeria. Asian Pac J Trop Biomed 2015;5:10.
21. Hamidi N, Ziane L, Djellouli M, Lazouni HA. Chemical characterization by GC-MS from the aerial parts of Fagonia longispina (Zygophyllaceae). Asian J Pharm Clin Res 2016;9:152-3.
This work is licensed under a Creative Commons Attribution 4.0 International License.
The publication is licensed under CC By and is open access. Copyright is with author and allowed to retain publishing rights without restrictions.