HAILEY-HAILEY DISEASE – A CASE REPORT

ANJALY P NAIR; SIBY JOSEPH; LAKSHMI R; SUNU KURIAN

doi:10.22159/ajpcr.2020.v13i9.38690

ANJALY P NAIR Department of Pharmacy Practice, St. Joseph’s College of Pharmacy, Cherthala, Kerala, India.
SIBY JOSEPH Department of Pharmacy Practice, St. Joseph’s College of Pharmacy, Cherthala, Kerala, India.
LAKSHMI R Department of Pharmacy Practice, St. Joseph’s College of Pharmacy, Cherthala, Kerala, India.
SUNU KURIAN Department of General Medicine, Lourdes Hospital, Post Graduate Institute of Medical Science and Research, Ernakulam, Kochi, Kerala, India.

DOI https://doi.org/10.22159/ajpcr.2020.v13i9.38690

Abstract

Hailey-Hailey disease (HHD) is a rare autosomal dominant skin condition discovered in 1939 by Hailey brothers. Prevalence is found to be around 1 in 50,000 and is relatively uncommon in India. First onset of disease occurs between 20 to 40 years of age, usually presented in the 3rd and 4th decades of life. Here, we report a case of a 50-year-old female who presented with clinical features of the HHD and showed greater response to the treatment.

Keywords: Familial pemphigus, Hailey-Hailey, ATP2C1 gene, Acantholysis, Dilapidated brick wall

References

1. Prateek K, Banwarilal MR, Chaudhary SS, Garg M. Hailey Hailey disease-a rare case report. Int J Res Dermatol 2016;2:36-9.
2. Sharma RL, Sharma R. Hailey-Hailey disease: Case report of a rare disease. IAIM 2018;5:94-8.
3. Yordanova I, Gospodinov DK. Familial benign chronic pemphigus (Hailey-Hailey disease). J IMAB Ann Proc Sci Papers 2007;13:60-2.
4. Graham PM, Melkonian A, Fivenson D. Familial benign chronic pemphigus (Hailey-Hailey disease) treated with electron beam radiation. JAAD Case Rep 2016;2:159-61.
5. Hassan I, Keen A. Hailey Hailey disease: A case report. Our Dermatol Online 2012;3:116.