ANTIMICROBIAL STUDIES OF DIFFERENT EXTRACTS OF HOLOPTELEA INTEGRIFOLIA (ROXB.) LEAVES

Authors

  • REKHA TRIPATHI Department of Applied Sciences, Maharaja Surajmal Institute of Technology, New Delhi, India.

DOI:

https://doi.org/10.22159/ajpcr.2020.v13i10.39057

Keywords:

Holoptelea integrifolia, Leaves, Extracts, Antimicrobial efficacy

Abstract

Objective: The aim of this study was to examine various extracts of leaves of Holoptelea integrifolia against some test bacteria and test fungi.

Methods: Disk diffusion method was adopted for the assessment of antimicrobial activity. Amikacin and nystatin were used as standard drugs for antibacterial and antifungal activity, respectively.

Results: The screening data indicated that all four extracts showed antibacterial activity against Staphylococcus aureus, but the growth of this bacteria was inhibited the most by the aqueous extract. In the case of antifungal efficacy, all the extracts inhibited the growth of almost all the test fungi. Petroleum ether and benzene extracts showed maximum efficacy against Aspergillus flavus, whereas methanolic extract and aqueous extract inhibited the growth of Rhizoctonia bataticola significantly.

Conclusion: Different extracts of leaves of H. integrifolia were significantly active against selected test fungi and they can be a harmless alternative of expensive conventional medicines.

Downloads

Download data is not yet available.

References

Alviano DS, Alviano CS. Plant extracts: Search for new alternatives to treat microbial diseases. Curr Pharm Biotechnol 2009;10:106-21.

Malini M, Abirami G, Hemalatha V, Annadurai G. Antimicrobial activity of ethanolic and aqueous extracts of medicinal plants against waste water pathogens. Int J Res Pure Appl Microbiol 2013;3:40-2.

Zhang R, Eggleston K, Rotimi V, Zeckhauser RJ. Antibiotic resistance as a global threat: Evidence from China, Kuwait and the United States. Global Health 2006;2:6.

Dorman HJ, Deans SG. Antimicrobial agents from plants: Antibacterial activity of plant volatile oils. J Appl Microbiol 2000;88:308-16.

Talib WH, Mahasneh AM. Antimicrobial, cytotoxicity and phytochemical screening of Jordanian plants used in traditional medicine. Mol 2010;15:1811-24.

Chopra RN, Nayar SL, Chopra IC. Glossary of Indian Medicinal Plants. New Delhi: CSIR; 1971.

Kirtikar KR, Basu BD. Indian Medicinal Plants. Vol. 3. Allahabad: Lalit Mohan Basu and Co.; 1975. p. 2292.

ICMR. Medicinal Plant of India. Vol. 2. New Delhi: ICMR; 1987. p. 48.

Hemadri K, Raj PV, Rao SB, Sharma CR. Folklore claims from Andhra Pradesh. J Sci Res Plant Med 1980;1:37-49.

Soujanya J, Silambujanaki P, Krishna VL. Anticancer efficacy of Holoptelea integrifolia, planch. Against 7, 12-dimethyl benz(a) anthracene induced breast carcinoma in experimental rats. Int J Pharm Pharm Sci 2011;3:103-6.

Tripathi RN, Tripathi RK, Pandey DK. Assay of antiviral activity in the crude leaf sap of some plants. Environ India 1981;4:86-7.

Sharma PV. Classical Uses of Medicinal Plants. Varanasi: Chaukhambha Orientalia; 1996.

Chandrasekar D, Madhusudhana K, Ramakrishna S, Diwan PV. Evaluation of antimicrobial, antioxidant and wound-healing potentials of Holoptelea integrifolia. J Ethnopharmacol 2008;115:249-56.

Sutar RC, Kasture SB, Kalaichelvan VK. Evaluation of anticonvulsant activity of leaf extract of Holoptelea integrifolia (Roxb) planch in experimental animals. Int J Pharm Pharm Sci 2014;6:308-11.

Gould JC, Bowie JH. The determination of bacterial sensitivity to antibiotics. Edinb Med J 1952;59:178-99.

Andrews JM. BSAC standardized disc susceptibility testing method. J Antimicrob Chemother 2001;4:43-57.

Published

07-10-2020

How to Cite

TRIPATHI, R. “ANTIMICROBIAL STUDIES OF DIFFERENT EXTRACTS OF HOLOPTELEA INTEGRIFOLIA (ROXB.) LEAVES”. Asian Journal of Pharmaceutical and Clinical Research, vol. 13, no. 10, Oct. 2020, pp. 191-3, doi:10.22159/ajpcr.2020.v13i10.39057.

Issue

Section

Original Article(s)