Review Paper SMOKING CARCINOGENS AND LUNG CANCERS- A REVIEW
Carcinogens and lung cancer
Smoking ambiguity contributes to a certain revelation regarding the process by which cancer is induced. In laboratory, carcinogens induce clear lung tumour to lung cancer induction. For instance, carcinogenic chemicals viz., 4(methylnitrosomine)-1-(3-pyridyl)-1-butanol (NNAL), nitrosonornicotine (NNN) etc. cause tumour malignancy. It is evident from the mechanistic studies that the carcinogens have stronger tendency to mutate the genes like suppresser gene, gene that encode the receptor of cell surface to the nucleus, thus, giving way to the proliferation of mutation leading to neo plastic cells. In this analysis article, we have discussed molecular mechanics that can cause cancer by nitrosamines like NNK and NNN regarding a variety of significant cigarette combustion carcinogens and the effort to introduce a different dimensional approach to the prevention of cancer, by understanding the perspective of various treatment.
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