• ANIL PRAKASH Department of Pharmacy, Bhupal Nobles’ College of Pharmacy, Udaipur, Rajasthan. https://orcid.org/0000-0002-8100-1878
  • YUVRAJ SINGH SARANGDEVOT Department of Pharmacy, Bhupal Nobles’ College of Pharmacy, Udaipur, Rajasthan.
  • BHUPENDRA VYAS Department of Pharmacy, Bhupal Nobles’ College of Pharmacy, Udaipur, Rajasthan.
  • SONALI ROY Department of Pharmacy, Bhupal Nobles’ College of Pharmacy, Udaipur, Rajasthan.




Free radicals, Phytochemicals, karkatshringi, Antioxidants, Ficus glomerata, Reactive oxygen species


Objective: This study is focused on the evaluation of phytochemical constituents and antioxidant properties contained in Ficus glomerata. Various phytochemical constituents such as alkaloid, glycoside, total phenolic content, flavonoid, and carbohydrate constituent content were evaluated.

Methods: Extraction of plant F. glomerata was obtained using methanol as solvent using soxhlation. Antioxidant properties in F. glomerata extract were evaluated using free radical scavenging activity using 2, 2-diphenyl-1-picrylhydrazyl method. Antioxidant activity of the extract of F. glomerata was expressed as gallic acid equivalent.

Results: The result obtained from the study was in support of the use of F. glomerata as a natural antioxidant against free radicals that are formed in the pathogenesis of many metabolic disorders.

Conclusion: The results obtained from the research found to conclude that antioxidant properties derived from natural extracts may be a promising alternative to synthetic oxidants and may aid in avoiding the side effects associated with the use of synthetic antioxidants. Other than the antioxidant properties, a correlation was observed between the total phenolic content and the antioxidant properties.


Download data is not yet available.


Channabasavaraj KP, Badami S, Bhojraj S. Hepatoprotective and antioxidant activity of methanol extract of Ficus glomerata. J Nat Med 2008;62:379-83. doi: 10.1007/s11418-008-0245-0, PMID 18431551

Eshwarappa RS, Iyer S, Subaramaihha SR, Richard SA, Dhananjaya BL. Antioxidant activities of Ficus glomerata (Moraceae) leaf gall extracts. Pharmacogn Res 2015;7:114-20. doi: 10.4103/0974-8490.147225, PMID 25598645

Verma AR, Vijayakumar M, Rao CV, Mathela CS. In vitro and in vivo antioxidant properties and DNA damage protective activity of green fruit of Ficus glomerata. Food Chem Toxicol 2010;48:704-9. doi: 10.1016/j.fct.2009.11.052, PMID 19951737

Supriya JG, Rohan SS, Neha MM, Minal RG, Sanjay DS. Antimicrobial activity of Ficus glomerata linn. Bark. Int Res J Pharm 2012;3:281-4.

Rahman M, Khatun A, Khan S, Khan A, Hossain F. Phytochemical, cytotoxic and antibacterial activity of two medicinal plants of Bangladesh ESI-MS: Hight thorughput screening and de-repilcation of natural products view project in vivo and in vitro screening of a racemosus for their anti-inflammatory acti. Pharmacologyonline 2014;1:3-10.

Yanishlieva NV, Marinova E, Pokorný J. Natural antioxidants from herbs and spices. Eur J Lipid Sci Technol 2006;108:776-93. doi: 10.1002/ejlt.200600127

Akhtar N, Ihsan-ul-Haq, Mirza B. Phytochemical analysis and comprehensive evaluation of antimicrobial and antioxidant properties of 61 medicinal plant species. Arab J Chem 2018;11:1223-35. doi: 10.1016/j.arabjc.2015.01.013

Tanzey SS, Mossine AV, Sowa AR, Torres J, Brooks AF, Sanford MS, et al. A spot test for determination of residual TBA levels in 18F-radiotracers for human use using Dragendorff reagent. Anal Methods 2020;12:5004-9. doi: 10.1039/d0ay01565b, PMID 33000785

Jha DK, Panda L, Lavanya P, Ramaiah S, Anbarasu A. Detection and confirmation of alkaloids in leaves of Justicia adhatoda and bioinformatics approach to elicit its anti-tuberculosis activity. Appl Biochem Biotechnol 2012;168:980-90. doi: 10.1007/s12010-012- 9834-1, PMID 22899014

Mulik R. One step synthesis of ZnO nanoparticles and their characterization. Int D J Sci DAV Int J Sci 2018;5536:1-5.

Chedea VS, Pop RM. Total polyphenols content and antioxidant DPPH assays on biological samples. In: Polyphenols in Plants: Isolation, Purification and Extract Preparation. 2nd ed. Netherlands: Elsevier Inc.; 2019. p. 169-83.

Marino D, Ribarova F, Atanassova M. Total phenolics and flavonoids in Bulgarian fruits and vegetables. J Univ Chem Technol Metall 2005;40:255-60.



How to Cite

PRAKASH, A., Y. S. SARANGDEVOT, B. VYAS, and S. ROY. “EXTRACTION AND CHARACTERIZATION OF FICUS GLOMERATA FOR ANTIOXIDANT ACTIVITY”. Asian Journal of Pharmaceutical and Clinical Research, vol. 15, no. 6, June 2022, pp. 46-50, doi:10.22159/ajpcr.2022.v15i6.44404.



Original Article(s)