DIABETES MELLITUS IN COVID-19; A HOSPITAL-BASED LONGITUDINAL ANALYTICAL STUDY
Keywords:Co-morbidities,, Outcome, LDH, CRP
Objectives: The aim of the study was (1) to assess and compare the profile of COVID-19 patients with diabetes and without diabetes and (2) to determine the outcome of COVID-19 patients with diabetes mellitus.
Methods: A hospital-based longitudinal analytical study was conducted on a total of 2000 patients in Bengaluru during the study period from August 2020 to July 2021. The patients fulfilling the inclusion criteria were enrolled for the study after obtaining informed consent. Patients were divided into diabetic and non-diabetic groups and inflammatory markers were compared between these two groups and outcome of these patients was noted.
Results: Of the 2000 COVID-19 patients included, 358 were diabetics in this study. Mean age of non-diabetic patients was 41.71 (±15.37) years and diabetic patients were 54.37 (±11.95) years. The inflammatory markers such as Lactate Dehydrogenase (LDH), Ferritin, C-Reactive Protein (CRP), and Neutrophil-Lymphocyte ratio (NLR) were significantly high in patients with diabetes compared to the non-diabetic patients with COVID-19 (p<0.05).
Conclusion: This study shows that diabetes is a major risk factor and contributes to the severity and mortality of patients with COVID-19. Our recommendations are for the strict glycemic control in patients affected by COVID-19 during treatment for the same.
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Copyright (c) 2022 Dr Avinash Rajanna, Dr Ravi K, Dr Abhiman Shetty, Dr Vaibhav S B, Dr Bhargav Bhat, Dr Yamini Marimuthu
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