SCREENING OF INVITRO ANTI-INFLAMMATORY ACTIVITY OF MICHELIA CHAMPACA LINN. FLOWERS

  • T. ananthi S.T.E.T Women's College, Bharathidasan University

Abstract

Objectives: Michelia champaca is an ayurvedic medicine which is used as anti-inflammatory agent. Therefore  our investigation was aimed to evaluate anti- inflammatory property of the flower extract of M.champaca by membrane stabilization method.

Methods: The prevention of hypotonicity induced human red blood cells(HRBC) membrane lysis was taken as a measure of the anti-inflammatory activity. The potency of the plant extract was compared with standard diclofenac sodium.

Results: Michelia champaca showed significant stabilizing activity of 57.4percent at concentration of 300 µg/ml. The percentage membrane stability exhibited by the extract was concentration dependent.

Conclusion: It can conclude that the methanolic extract of M.champaca posses significant invitro anti-inflammatory activity.

Key words: Michelia champaca, hypotonic, membrane stabilization,diclofenac sodium 

Author Biography

T. ananthi, S.T.E.T Women's College, Bharathidasan University
Biochemistry

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How to Cite
ananthi, T. “SCREENING OF INVITRO ANTI-INFLAMMATORY ACTIVITY OF MICHELIA CHAMPACA LINN. FLOWERS”. Asian Journal of Pharmaceutical and Clinical Research, Vol. 6, no. 9, Nov. 2013, pp. 71-72, https://innovareacademics.in/journals/index.php/ajpcr/article/view/553.
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