BUCHANANIA LANZAN SPRENG.: A VERITABLE STOREHOUSE OF PHYTOMEDICINES
Buchanania lanzan Spreng, a dry deciduous forest tree of family Anacardiaceae is widely used by Indian tribes for treating various diseases. Three
major chemical constituents of potent medicinal value, namely celidoniol, vomicine, epinitol have been characterized from an organic extract of
leaves. Such extracts mainly exhibit antidiabetic, antihyperlipidemic, antioxidant, anti-inflammatory, wound healing, antidiarrheal, antivenom activity
including a host of other curative properties. Very recently, unique biomaterials and biofilms are being extracted from seeds, which promise to become
a major contributor in pharmaceutical industry. This review attempts to present thorough updated account of ongoing and emerging areas of research
of this plant, especially in the field of phytomedicnes and pharmaceuticals.
Keywords: Buchanania lanzan, Phytochemicals, Curative properties, Phytomedicine.
1. Zeven AC, de Wet JM. Dictionary of cultivated plants and their regions of diversity: Excluding most ornamentals, forest trees and lower plants. Pudoc Wageningen 1982;2:227.
2. Warrier PK, Nambiar VP, Ramakutty C. Indian Medicinal Plants: A Compendium of 500 Species. Vol. 1. Delhi: Orient Black Swan; 1994. p. 310.
3. Singh J, Patra AK, Nandeshwar DL, Meshram PB, Negi KS. Effect of growth regulators on the rooting of root cuttings of Chironji (Buchanania lanzan Spreng). Proceedings of National Workshop on Conservation of Medicinal Plants; 2002. p. 128.
4. Rai YC. Buchanania lanzan Spreng: Studies on methods of propagation and estimation of fruit yield. Indian Forester 1982;108(7):501-11.
5. Chadhar SK, Sharma MC. Trends in fruit production in Buchanania lanzan trees, Vaniki Sandesh 1997;21:1-3.
6. Sharma A. Scientific harvesting for quality seed collection of Buchanania lanzan Spreng for its conservation and sustainable management â€“ Case study of Chhindwara, Madhya Pradesh, India. Int J Bio Sci Bio Technol 2012;4(1):65-74.
7. Nasim KT, Arya R, Babu V, Ilyas M. Myricetin 3â€²-rhamnoside-3-galactoside from Buchanania lanzan (anacardiaceae). Phytochemistry 1992;31(7):2569-70.
8. Mehta SK, Mukherjee S, Jaiprakash B. Preliminary phytochemical investigation on leaves of Buchanania lanzan (Chironji). Int J Pharm Sci Rev Res 2010;3(2):55-9.
9. Mehta SK, Jaiprakash B, Nayeem N. Isolation and phytochemical investigation on leaves of Buchanania lanzan (Chironji). Ann Biol Res 2011;2(3):469-73.
10. Khare CP. Indian Medicinal Plants: An Illustrated Dictionary. Berlin Heidelberg New York: Springer; 2007. p. 104.
11. Sengupta A, Roychoudhury SK. Triglyceride composition of Buchanania lanzan seed oil. J Sci Food Agric 1977;28(5):463-8.
12. Sharma N, Ghosh R, Nigam M. Toxigenic fungi associated with stored fruits of Chironji. Indian Phytopathol 1998;51:284-6.
13. Shende S, Raj M. Multiple shoot formation and plant regeneration of a commercially-useful plant, Buchanania lanzan (Spreng). Plant Biotechnol 2005;22(1):59-61.
14. Sharma P, Koche V, Quraishi A, Mishra SK. Somatic embryogenesis in Buchanania lanzan Spreng. In Vitro Cell Dev Biol 2005;41:645-7.
15. Capuano C, Piccioni E, Standardi A. Effect of different treatments on the conversion of M.26 apple rootstock synthetic seeds obtained from encapsulated apical and axillary micropropagated buds. J Hort Sci 1998;73:299-305.
16. Singh AK, Chand S. Plant regeneration from alginate encapsulated somatic embryos of Dalbergia sissoo Roxb. Indian J Biotechnol 2010;9:319-24.
17. Chand S, Singh AK. Plant regeneration from encapsulated nodal segments of Dalbergia sissoo Roxb. a timber yielding leguminious tree species. J Plant Physiol 2004;161:237-43.
18. Hung CD, Trueman SJ. Alginate encapsulation of shoot tips and nodal segments for short-term storage and distribution of the eucalypt Corymbia torelliana x C. citriodora. Acta Physiol Plant 2011;34:117â€‘28.
19. Available from: http://www.envis.frlht.org/trade_search.php?txtpart=SEEDS&lst_part=SEEDS&txttrade=AALI&lst_trade=CHIRONJI.
20. Warokar AS, Ghante MH, Duragkar NJ, Bhusari KP. Anti-inflammatory and antioxidant activities of methanolic extract of Buchanania lanzan Kernel. Indian J Pharm Educ Res 2010;44(4):363-8.
21. Mehta KS, Mukherjee S, Jaiprakash B. Anti-inflammatory activity of the methanolic extract of Buchanania lanzan leaves by Carrageenan-induced rat paw oedema method. Int J Pharm Sci Rev Res 2011;6(2):144â€‘6.
22. Patsnaik AK, Kodati D, Pareta SK, Patra KC, Harwansh RK. Analgesic and anti-inflammatory activities of Buchanania lanzan Spreg. roots. Res J Pharm Biol Chem Sci 2011;2(1):419-25.
23. Sekhar S, Karmakar R, Harishchandra SP. Curative properties of Buchanania lanzan: As evaluated by its anti-oxidant, anti-inflammatory and DNA protective properties. J Nat Pharm 2012;3(2):71-7.
24. Patra KC, Pareta SK, Harwansh RK, Kumar KJ. Antioxidant activity of Buchanania lanzan Spreg. F: Anacardiaceae. Pharmacol Online 2011;1:733-9.
25. Sushma N, Smitha PV, Venu Gopal Y, Vinay R, Reddy NS, Mohan CM, et al. Antidiabetic, antihyperlipidemic and antioxidant activities of Buchanania lanzan Spreng methanol leaf extract in streptozotocin-induced Types I and II diabetic rats. Trop J Pharm Res 2013;12(2):221â€‘6.
26. Gandhi HR. Diabetes and coronary artery disease Importance of risk factors. Cardiol Today 2001;1:31-4.
27. Kamesawara BR, Giri R, Kesavulu MM, Apparao CH. Effect of oral administration of bark extracts of Pterocarpus santalinus L. on blood glucose level in experimental animals. J Ethnopharmacol 2001;74(1):69-74.
28. Alexander P, Wikman G. Effects of adaptogens on the central nervous system and the molecular mechanisms associated with their stress: Protective activity. Pharmaceuticals 2010;3(1):188-224.
29. Mehta KS, Nayeem N, Bains N. Adaptogenic activity of methanolic extract of Buchanania lanzan leaves an experimental study in rat model. Pharm Sinica 2011;2(3):107-12.
30. Abeer H, Rahim AE, Hafiz NA. Investigation on the protective effect of grape seed and linseed oils against cyclophosphamide induced genotoxicity in mice. Glob Vet 2009;3(5):377-82.
31. Qari SH. In vitro evaluation of the antimutagenic effect of Origanum majorana extract on the meristemetic root cells of Viciafaba. J Tibah Uni Sci 2008;1:6-11.
32. Jain R, Jain. SK. Effect of Buchanania lanzan Spreng. Bark extract on cyclophosphamide induced genotoxicity and oxidative stress in mice. Asian Pac J Trop Med 2012;5(3):187-91.
33. Fontaine O. Bacterial diarrhoea and treatment. Lancet 1988;331:1234â€‘5.
34. Kodati D, Pareta SK, Patnaik A. Antidiarrhoeal activity of alcoholic extract of Buchanania lanzan Spreg. roots. Pharmacol Online 2010;3:720-6.
35. Kodati D, Pareta S, Patra KC. Antiulcer activity of ethanolic extract of Buchanania lanzan Spreg. roots. Ann Biol Res 2010;1(4):234-9.
36. Chitra V, Dharani PP, Pavan KK, Narayana RA. Wound healing activity of alcoholic extract of Buchanania lanzan in albino rats. Int J Chem Tech Res 2009;1(4):1026-31.
37. Mehta BK, Pattnaik A, Kumar A. Enhancement and validation of wound healing activity with herbal gel formulated from sub-fraction of Buchnania lanzan Spreng. bark extract. Int J Pharm PharmSci 2014;6(7):281-6.
38. Reddy DS. Assessment of nootropic and amnestic activity of centrally acting agents. Indian J Pharmacol 1997;29:208-21.
39. Ellen YS, Kathryn MU. Donepezil: Anti cholinesterase inhibitor for Alzheimerâ€™s disease. Am J Health Syst Pharm 1997;54:2805-10.
40. Neelakanth MJ, Bhat MR, Taranalli AD, Veeresh B. Effect of Buchanania lanzan seeds on learning and memory in normal and memory deficit rats. J Res Pharm Biomed 2012;22(1):33-8.
41. Minu V, Harsh V, Ravikant T, Paridhi J, Noopur S. Medicinal plants of chhattisgarh with anti-snake venom property. Int J Curr Pharm Rev Res 2012;3(2):1-10.
42. Hegde K, Naseeb KM, Syed A, Deepak TK. Kalangottil A. Evaluation of antivenom activity of ethanolic extract of Buchanania lanzan bark against Naja kaouthia snake venom. Unique J Pharm Biol Sci 2014;2(2):39-45.
43. Hullatti K, Manjunatha JR, Kuppasth IJ. Comparative study on diuretic effect of Buchanania angustifolia Roxb. and Buchanania lanzan Spreng. fruit extracts and fractions. J Appl Pharm Sci 2014;4(8):059â€‘63.
44. Tyagi N. A novel, potent, bio-film former from the seeds of Buchanania lanzan for formulating tobramycin occuserts. Int J Pharm Tech Res 2012;4(1):422-6.
45. Tyagi N, Madhav NV. Formulation and evaluation of zidovudine micro emulsion using a novel bio polymer from the seeds of Buchanania lanzan. Int J Biopharm 2012;3(1):40-3.
46. Singh S, Bothara BS, Ayaz A. Formulation of oral mucoadhesive tablets using mucilage isolated from Buchanania lanzan spreng seeds. Int J Pharm Sci Nanotechnol 2014;7(2):2494-503.
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