• Finna Setiawan
  • Ketut Adnyana I
  • Elin Yulinah Sukandar
  • Sukrasno
  • Ari Yuniarto Bandung Institute of Technology
  • Resny Pebritrinasari


Objective: The objective of this research was to screening potency of anti-obesity effect and antioxidant activity from Sapindus rarak Pulp., Punica
granatum Leaves, Jasminllum sambac Flos., Tamarindus indica Pulp., and Senna alexandrina Leaves.
Methods: This study was performed through in-vitro method to determine the potency of anti-obesity, such as its ability to inhibit pancreatic lipase
activity and radical-scavenging activity against free radicals like 1,1-diphenyl-2-picrylhydrazyl to determine the potency of these plants as antioxidant.
Results: The 50% inhibitory concentration of pancreatic lipase activity inhibitory and antioxidant activity consecutively, P. granatum Leaves
(20.64 ppm; 77.89 ppm), J. sambac Flos. (53.46 ppm; 127.95 ppm), T. indica Pulp. (62.02 ppm; 159.16 ppm), S. alexandrina Leaves (94.69 ppm;
142.28 ppm), and S. rarak Pulp. (796.32 ppm; 147.56 ppm).
Conclusion: P. granatum Leaves showed the best potency of anti-obesity compared to other plants based on its ability to inhibit pancreatic lipase
activity and antioxidant activity.
Keywords: Anti-obesity, Pancreatic lipase activity, Antioxidant.

Author Biography

Ari Yuniarto, Bandung Institute of Technology

School of Pharmacy and Rank of 125 in Southeast Asia (2014)


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How to Cite
Setiawan, F., K. Adnyana I, E. Yulinah Sukandar, Sukrasno, A. Yuniarto, and R. Pebritrinasari. “PHARMACOLOGICAL SCREENING FOR POTENCY OF ANTIOBESITY ON FIVE PLANTS BASED ON ETHNOPHARMACOLOGICAL USE”. Asian Journal of Pharmaceutical and Clinical Research, Vol. 8, no. 4, July 2015, pp. 299-01,
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