@article{Jith_Kumar_Joy_P_R_2016, title={A PROSPECTIVE STUDY OF DRUG–DRUG INTERACTIONS AND ADVERSE DRUG REACTIONS AMONG STROKE PATIENTS IN A TERTIARY CARE HOSPITAL}, volume={9}, url={https://journals.innovareacademics.in/index.php/ajpcr/article/view/13651}, DOI={10.22159/ajpcr.2016.v9s3.13651}, abstractNote={<p>ABSTRACT<br />Objective: Our study attempts to get an insight into the drug–drug interactions (DDIs) and adverse drug reactions (ADRs) among stroke patients from<br />the Neurology Department in a private hospital.<br />Methods: In a prospective study spanning 6 months (May to October 2015), we have analyzed the prescription data of 221 patients with both<br />ischemic and hemorrhagic stroke. Gender, age, social habits, length of stay, drug utilization pattern, DDIs reported from the database and clinically<br />observed, and ADRs of individual drugs were observed among the patients. Of 221 cases, 208 (94.11%) were ischemic, 12 (5.43%) were hemorrhagic,<br />and 1 (0.45%) was transient ischemic attack.<br />Results: A number of 140 patients were males and 80 were females. The mean age of the patients was between 41 and 70 years. In ischemic patients,<br />357 major, 282 moderate, and 38 mild DDIs were reported using a specific database, while in hemorrhagic patients, 10 major, 7 moderate, and 1 mild<br />interaction were reported using a specific database. 18 DDIs were observed clinically and confirmed with evidence. 8 DDI-induced ADRs and 10 ADRs<br />caused by individual drugs were observed in our study population. 18 DDIs were observed clinically and confirmed with evidence. 8 DDI-induced<br />ADRs and 10 ADRs caused by individual drugs were observed in our study population.<br />Conclusion: Drugs if wrongly prescribed may cause negative outcomes and pose significant challenge to health-care providers and may contribute to<br />morbidity and mortality. Clinical pharmacist can play an important role in identifying and resolving drug-related problems through pharmaceutical<br />care practices.<br /><strong>Keywords</strong>: Stroke, Drug–drug interactions, Adverse drug reactions, Clinical pharmacist.</p>}, number={9}, journal={Asian Journal of Pharmaceutical and Clinical Research}, author={Jith, Athira and Kumar, Chaithanya T and Joy, Joffey Sara and P, Kavitha Samy and R, Sambath Kumar}, year={2016}, month={Dec.}, pages={100–104} }