@article{BANUKUMAR_I_Rg_2017, title={FLUOROQUINOLONE RESISTANCE PATTERN AMONG THE PATHOGENS CAUSING URINARY TRACT INFECTION IN A TERTIARY CARE HOSPITAL IN KANCHIPURAM DISTRICT, TAMIL NADU, INDIA}, volume={10}, url={https://journals.innovareacademics.in/index.php/ajpcr/article/view/20678}, DOI={10.22159/ajpcr.2017.v10i11.20678}, abstractNote={<p class="Default"> </p><p class="Pa7"> <strong>Objective: </strong>The aim is to study the fluoroquinolone resistance pattern among the pathogens causing urinary tract infection (UTI).</p><p class="Pa7"><strong>Methods: </strong>This study was done during January to July 2016 in Tagore Medical College including both hospitalized and out patients. During this 7-month study, around 2695 urine samples were analyzed for the evidence of UTI. 718 samples were culture positive. 366 samples showed fluoroquinolones resistance (50.9%). They were screened for all fluoroquinolone drugs by doing antimicrobial susceptibility testing by Kirby-Bauer disc diffusion method as per the Clinical and Laboratory Standards Institute CLSI guidelines.</p><p class="Pa7"><strong>Results: </strong>The resistance pattern of different isolates to norfloxacin is <em>Klebsiella pneumoniae </em>- 20%, <em>Escherichia coli </em>- 51.4%, Enterococci - 11.1%, <em>Proteus mirabilis </em>- 50%, and <em>Staphylococcus saprophyticus </em>- 37.5%; For nalidixic acid is <em>K pneumoniae </em>- 25%, <em>E. coli </em>- 6.8%, <em>Pseudomonas aeruginosa </em>- 71.4%, Enterococci - 11.1%, <em>P. mirabilis </em>- 25%, and <em>S. saprophyticus </em>- 25%; For ciprofloxacin is <em>K. pneumoniae </em>- 5%, <em>E. coli </em>- 5.4%, <em>P. mirabilis </em>- 25%, and <em>S. saprophyticus - </em>25%; and For ofloxacin is <em>K. pneumoniae </em>- 10%, <em>E. coli </em>- 5.4%, Enterococci 11.1%, and <em>S. saprophyticus </em>62.5%.</p><p><strong>Conclusion: </strong>Due to increasing resistance to fluoroquinolones in many hospitals and to make the developing resistance rates under control, empirical usage of it is either abandoned or should be restricted.</p>}, number={11}, journal={Asian Journal of Pharmaceutical and Clinical Research}, author={BANUKUMAR, Shanthi and I, Kannan and Rg, Sukumar}, year={2017}, month={Nov.}, pages={292–294} }