@article{Marbun_Sitorus_Sinaga_2018, title={ANTIDIABETIC EFFECTS OF PUMPKIN (CUCURBITA MOSCHATA DURCH) FLESH AND SEEDS EXTRACTS IN STREPTOZOTOCIN INDUCED MICE}, volume={11}, url={https://journals.innovareacademics.in/index.php/ajpcr/article/view/22023}, DOI={10.22159/ajpcr.2018.v11i2.22023}, abstractNote={<p class="Pa7"> <strong>Objective: </strong>The present study is to investigate the antidiabetic effect of pumpkin flesh and seeds ethanolic extracts in STZ-induced diabetic mice.</p><p class="Pa7"><strong>Methods: </strong>The study begins with making the ethanolic extracts of pumpkin flesh and seeds and then evaluates the physicochemical characterization, phytochemical screening, and induced diabetic mice using STZ.</p><p class="Pa7"><strong>Result: </strong>The physicochemical evaluation shows that the extracts had a good and high purity level, while the phytochemical screening showed both pumpkin flesh and seeds extracts have a various of phytoconstituents. The pumpkin flesh and seeds ethanolic extracts (dose level 150 mg/kg) showed a significant reduction of the blood glucose.</p><p><strong>Conclusion: </strong>Pumpkin flesh and seeds ethanolic extracts exhibited significant antidiabetes activity in STZ-induced mice.</p>}, number={2}, journal={Asian Journal of Pharmaceutical and Clinical Research}, author={Marbun, Novarianti and Sitorus, Panal and Sinaga, Siti Morin}, year={2018}, month={Feb.}, pages={91–93} }