@article{Sianipar_Suwarso_Rosidah_2018, title={ANTIOXIDANT AND ANTICANCER ACTIVITIES OF HEXANE FRACTION FROM CARICA PAPAYA L. MALE FLOWER}, volume={11}, url={https://journals.innovareacademics.in/index.php/ajpcr/article/view/22382}, DOI={10.22159/ajpcr.2018.v11i3.22382}, abstractNote={<p class="Pa7"> <strong>Objective: </strong>This study examined the antioxidant and anticancer potential activities of the hexane fraction from the male flower of <em>Carica papaya </em>L., which is long been known to be a very important source of nutraceutical and pharmaceutical.</p><p class="Pa7"><strong>Methods: </strong>Standard fractioned (fraction) method with phytochemical screening. The antioxidant activity was carried out using the α,α-diphenyl-β- picrylhydrazyl method and the anticancer potential activity was carried out using 3-(4,5-dimethythiazol-. 2-yl)-2,5-diphenyl tetrazolium bromide assay to check the cytotoxic activity on WiDr (colon cancer cell) and Vero cell (normal cell).</p><p class="Pa7"><strong>Result: </strong>Phytochemical screening of the hexane fraction from the male flower of papaya shows a strong sign of triterpenoids and steroids; while the IC50 of antioxidant value was 100.81±1.180 μg/ml. Cytotoxic effect shows that the hexane fraction of papaya male flower had selectivity to WiDr cell (colon cancer cell).</p><p><strong>Conclusion: </strong>This study provides evidence that <em>C. papaya </em>L. male flower possesses antioxidant activity, as well as cytotoxic and chemopreventive properties. It might be beneficial as medicinal plant as an antioxidant and anticancer nutraceutical and pharmaceutical sources.</p>}, number={3}, journal={Asian Journal of Pharmaceutical and Clinical Research}, author={Sianipar, Masria Phetheresia and Suwarso, Edy and Rosidah, Rosidah}, year={2018}, month={Mar.}, pages={81–83} }