@article{Zaidan_Debby Bp_Abdillah_2018, title={THE EFFECT OF SAUCE OF L. LEUCOCEPHALA SEEDS (LEUCAENA LEUCOCEPHALA [LAM.] DE WIT) ON LOWERING BLOOD GLUCOSE IN HYPERGLYCEMIC MICE}, volume={11}, url={https://journals.innovareacademics.in/index.php/ajpcr/article/view/26570}, DOI={10.22159/ajpcr.2018.v11s1.26570}, abstractNote={<p class="Pa8"> <strong>Objective: </strong>The research to investigate that the source of <em>Leucaena leucocephala </em>can lower blood glucose levels in hyperglycemic mice.</p><p class="Pa8"><strong>Methods: </strong>In this study, 42 mice were divided into 7 groups each consisted of 6 mice: Normal Group I, Group II (metformin positive control), Group III (negative control), Group IV (sauce of <em>L. leucocephala </em>at a dose of 0.1 ml), Group V (sauce of <em>L. leucocephala </em>at a dose of 0.2 ml), Group VI (sauce of <em>L. leucocephala </em>with doses of 0.4 ml), and Group VII (sauce of <em>L. leucocephala </em>at a dose of 0.8 ml). The dosage of Group II, IV, V, VI, and VII was orally administered. Blood glucose levels in mice were observed during normal conditions and after administration of 200 mg/kg bw alloxan intraperitoneally (alloxan-induced mice). On day 0, 3, 7, and 14, blood was taken from the tail and glucose levels were measured with a glucometer.</p><p class="Pa8"><strong>Results: </strong>Data were analyzed by one-way analysis of variance followed by LSD test. Based on the results, the sauce at a dose of 0.8 ml was able to lower the blood glucose levels up to normal blood glucose levels.</p><p><strong>Conclusion: </strong>There was not significantly different between the groups given sauce of <em>L. leucocephala </em>at a dose of 0.8 ml with the group given metformin (positive control).</p>}, number={13}, journal={Asian Journal of Pharmaceutical and Clinical Research}, author={Zaidan, Sarah and Debby Bp, Ria and Abdillah, Syamsudin}, year={2018}, month={Apr.}, pages={70–72} }