@article{Hepsibah A_G_2015, title={IN VITRO ANTIBACTERIAL ACTIVITY AND PHYTOCHEMICAL ANALYSIS OF ORMOCARPUM COCHINCHINENSE EXTRACTS ON NOSOCOMIAL INFECTION CAUSING BACTERIA}, volume={8}, url={https://journals.innovareacademics.in/index.php/ajpcr/article/view/3231}, abstractNote={<p>Objective: The present study was aimed at evaluating the antibacterial activity and phytochemical analysis of the leaf extracts of Ormocarpum<br />cochinchinense.<br />Methods: The leaf powder was extracted by sequential extraction method using chloroform, acetone, and methanol. Preliminary phytochemical<br />analysis of the extracts was done using standard methods. The dried extracts were screened for antibacterial activity using disk diffusion method and<br />the minimum inhibitory concentration (MIC) method.<br />Results: The acetone extract showed the presence of flavonoids, tannins, steroids, phlobatannins, and saponins. Methanol extract contained<br />flavonoids, tannins, phlobatannins, saponins, and terpenoids. The chloroform extract contained steroids. The chloroform extract did not show any<br />activity, whereas the acetone extract showed significant activity against all the bacteria with a MIC value of 0.080 mg/ml against Escherichia coli<br />(ATCC 25922) and Klebsiella pneumoniae (ATCC 15380) and 0.18 mg/ml against Staphylococcus aureus (meticillin resistant). The methanol extract<br />showed very less activity.<br />Conclusion: The present study has proved the antibacterial potency of O. cochinchinense for the first time. This plant is a potential source of<br />antimicrobial agents of the future.</p><p>Keywords: Antibacterial activity, Phytochemical analysis, Minimum inhibitory concentration, Ormocarpum cochinchinense, Acetone extract.</p>}, number={1}, journal={Asian Journal of Pharmaceutical and Clinical Research}, author={Hepsibah A, Hannah and G, Jeya Jothi}, year={2015}, month={Jan.}, pages={113–116} }