@article{A SIDDIQUI_ANSARI_2015, title={THERAPEUTIC EFFECT OF A UNANI FORMULATION ON HBsAg IN CHRONIC HEPATITIS B: A CASE SERIES}, volume={8}, url={https://journals.innovareacademics.in/index.php/ajpcr/article/view/6175}, abstractNote={<p>Objectives: Chronic hepatitis B (CHB) is a major health concern in terms of its high prevalence, as well as restricted, and costly health care resources<br />in India. The physicians of the Unani system of Medicine have been treating hepatitis since centuries. The purpose of our study was to assess the effect<br />of Unani Formulation in the treatment naïve, CHB cases and to collect data to warrant further clinical trials.<br />Methods: We conducted a case series with five patient of CHB, subsequently treated with the Unani formulation. Cases were confirmed with standard<br />hepatitis antigen and viral measurements. The patients were treated for 6 months with measurement of the hepatitis B surface antigen (HbsAg).<br />Results: Loss of surface antigen occurred in the patients and became HbsAg negative within an average 13 weeks of treatment.<br />Discussion: We reviewed the literature related to the Unani formulation used for the treatment in this study. Its constituents have exhibited antiviral,<br />anti-inflammatory, immunomodulatory, hepatoprotective and antioxidant properties, suggesting possible mechanisms of action in the CHB.<br />Conclusion: The preliminary findings indicate the potential therapeutic role of the Unani formulation in the treatment of CHB. Clinical trials based on<br />this Unani pharmacopeal formulation should be conducted to explore the therapeutic potential of this formulation in CHB.<br />Keywords: Chronic hepatitis B, Unani Medicine, Unani formulation, Complementary Medicine, Herbal antivirals, Hepatoprotective, Warme jigar, Viral<br />hepatitis.</p><p> </p>}, number={5}, journal={Asian Journal of Pharmaceutical and Clinical Research}, author={A SIDDIQUI, MOHAMMAD and ANSARI, SHABNAM}, year={2015}, month={Sep.}, pages={77–79} }