TY - JOUR AU - Rahman, Habibur AU - K, Manjula AU - T, Anoosha AU - K, Nagaveni AU - Eswaraiah, M. Chinna AU - Bardalai, Dipankar PY - 2013/07/01 Y2 - 2024/03/29 TI - IN-VITRO ANTI-OXIDANT ACTIVITY OF CITRULLUS LANATUS SEED JF - Asian Journal of Pharmaceutical and Clinical Research JA - Asian J Pharm Clin Res VL - 6 IS - 3 SE - Articles DO - UR - https://journals.innovareacademics.in/index.php/ajpcr/article/view/148 SP - 152-157 AB - <p><strong>Objective:</strong> The objective of present work is to study the <em>In-vitro </em>anti-oxidant activities of n-Hexane, Chloroform and Ethanol extract of <em>Citrullus lanatus </em>seeds to find out the extract having highest anti-oxidant activity.  <strong>Material and Methods:</strong> The <em>In-vitro </em>anti-oxidant activity of the extracts were studied using 1,1-diphenyl-2-picryl hydrazyl (DPPH) radical scavenging activity, Ferric reducing power activity, Hyderogen peroxide(H<sub>2</sub>O<sub>2</sub>) scavenging activity and Nitric Oxide(NO) scavenging activity. The total Phenolic contents and Flavanoid contents were estimated taking Gallic Acid and Quercetin calibration curve respectably. <strong>Results:</strong> In <em>In-vitro </em>anti-oxidant studies it was found that all the extracts posses <em>In-vitro </em>anti-oxidant activities. But the order of possessing activities were n-hexane&gt;ethanol&gt;chloroform extracts of <em>Citrullus lanatus </em>seeds. The total Phenolic content was highest in n-hexane extract and Total Flavanoid content was highest in ethanol extract.  <strong>Conclusion:</strong> It can be concluded that <em>Citrullus lanatus</em>seed extracts possess anti-oxidant activities and the potency of anti-oxidant activities depends on the type of extract. The n-hexane extract of <em>Citrullus lanatus </em>seeds possess highest anti-oxidant activity <em>in-vitro.</em></p> <p><strong>Keywords: </strong><em>Citrullus lanatus, In-vitro </em>anti-oxidant, 1,1-diphenyl-2-picryl hydrazyl (DPPH), Total Phenolic Content, <strong></strong></p> ER -