TY - JOUR AU - m, Manigandan AU - K, Kolanjinathan PY - 2016/12/01 Y2 - 2024/03/28 TI - QUALITATIVE PHYTOCHEMICAL SCREENING AND ANTIOXIDANT ACTIVITY OF ELYTRARIA ACAULIS LINDAU (ACANTHACEAE) Research Article JF - Asian Journal of Pharmaceutical and Clinical Research JA - Asian J Pharm Clin Res VL - 9 IS - 9 SE - Original Article(s) DO - 10.22159/ajpcr.2016.v9s3.15759 UR - https://journals.innovareacademics.in/index.php/ajpcr/article/view/15759 SP - AB - <p>ABSTRACT<br />Objectives: To analyze the phytochemicals quantitatively and screening the antioxidant efficacy of methanol extracts of Elytraria acaulis plant extract<br />by in vitro.<br />Methods: The total phenols, flavonoids, and tannin contents analyzed by Folin-Ciocalteu method, aluminum chloride colorimetric and calculated as<br />gallic acid equivalents/g (GAE/g) of dry weight. Free radical scavenging activity was screened using 1,1-diphenyl-2-picrylhydrazyl (DPPH), radical<br />scavenging activities, and ferric reducing power assay was also analyzed.<br />Results: The total phenolic content of the aqueous leaf extract was 46.84 µg GAE/g of extract powder. Significantly similar levels of total flavonoid and<br />tannin contents of the plant were 41.72 and 39.50 µg GAE/g, respectively. The plant extracts showed appreciable free radical scavenging activities at<br />the highest concentration of 400 µg/mL superoxide anion radical with IC<br /> values (107.7±1.081 µg/mL), and for DPPH and considerably high amount<br />of radical scavenging activity was found with very low IC<br />50<br />50<br /> values (4.3±0.88 µg/mL) compared with quercetin.<br />Conclusion: The phenolic and flavonoid compounds provide substantial antioxidant properties which could be effectively used for pharmaceutical,<br />nutraceutical as well as anti-inflammatory applications.<br />Keywords: Phenols, Flavonoids, 1,1-diphenyl-2-picrylhydrazyl, Pharmaceuticals.</p> ER -