TY - JOUR AU - Muhtadi, Ahmad AU - Irenka, Yola AU - Ayu, Wulan Chandra AU - Hendriani, Rini AU - Zuhrotun, Ade PY - 2017/05/01 Y2 - 2024/03/29 TI - HYPOGLYCEMIC ACTIVITY OF TEN MEDICINAL PLANTS EXTRACT IN GLUCOSE INDUCED MICE JF - Asian Journal of Pharmaceutical and Clinical Research JA - Asian J Pharm Clin Res VL - 10 IS - 14 SE - Original Article(s) DO - 10.22159/ajpcr.2017.v10s2.19473 UR - https://journals.innovareacademics.in/index.php/ajpcr/article/view/19473 SP - 14-17 AB - <p><strong>Objective:</strong> To evaluate and compare the hypoglycemic activity of ten medicinal plantsextract that are used empirically to treat hyperglycemia in Indonesia, in order to determineplant with the most potential as a hypoglycemic agent.</p><p><strong>Methods:</strong> Activity test was conducted in Swiss Webster glucose induced mice with glucosetolerance test. The ethanolic extracts of <em>Mangiferaindica</em> L. leaves, <em>Perseaamericana</em> Mill.leaves, <em>Acoruscalamus</em> L. rhizome, <em>Phyllanthusniruri</em> L. herb, <em>Syzigiumcumini</em> (L.) skeelsbark, <em>Zingiberofficinale</em> Roscoe rhizome, <em>Moringaoleifera</em> Lam. leaves, <em>Tamarindusindica</em>L. seed, <em>Momordicacharantia</em> L. fruits and <em>Azadirachtaindica</em> A. juss leaves, which weregiven orally at the same dose of 300 mg/kg bw. The blood samples wereused for determination of glucose level examination using glucose meter and test strips (AccuChek).</p><p><strong>Results:</strong> The ethanolic extract of <em>Mangiferaindica</em> L. leaves has the best activity in reductionof blood glucose level in mice, followed by <em>Zingiberofficinale</em> Roscoe rhizome,<em>Acoruscalamus</em> L. rhizome, <em>Tamarindusindica</em> L. seed.,<em>Momordicacharantia</em>L. fruit., <em>Syzigiumcumini</em> (L.) skeels bark, <em>Phyllanthusniruri</em> L. herb., <em>Perseaamericana</em> Mill. leaves, and<em>Azadirachtaindica</em> A. juss leaves.</p><p><strong>Conclusion:</strong> Results of the present study suggest the potential use of <em>Mangiferaindica</em> L.leaves extract in therapy of hyperglycemia.</p><p> </p> ER -