TY - JOUR AU - GAJENDRA NATH MAITY, AU - JOY SARKAR, AU - SOMANJANA KHATUA, AU - SOUMITRA MONDAL, AU - KRISHNENDU ACHARYA, PY - 2019/07/07 Y2 - 2024/03/28 TI - GREEN SYNTHESIS OF SILVER NANOPARTICLES USING MANGROVE FRUIT POLYSACCHARIDE FOR BACTERIAL GROWTH INHIBITION: GREEN SYNTHESIS OF SILVER NANOPARTICLES JF - Asian Journal of Pharmaceutical and Clinical Research JA - Asian J Pharm Clin Res VL - 12 IS - 7 SE - Original Article(s) DO - 10.22159/ajpcr.2019.v12i7.33681 UR - https://journals.innovareacademics.in/index.php/ajpcr/article/view/33681 SP - 179-183 AB - <p><strong>Objective: </strong>The objective of this study was to find out the antibacterial activity of the silver nanoparticles (Ag-NPs) using a low-cost green synthesis approach for the formulation of Ag-NPs applying polysaccharide extracted from the fruits of a mangrove plant of Sundarban.</p><p><strong>Methods: </strong>Fresh and healthy fruits were collected from <em>Ceriops decandra </em>plant. Sufficient amount of carbohydrates was extracted from those fruits and the physicochemical characterization of the polysaccharide was analyzed by gas chromatography–mass spectrometry and Fourier-transform infrared spectrophotometry. The respective polysaccharide was further applied to generate the Ag-NPs which were characterized by UV visible, dynamic light scattering, transmission electron microscopy, EDAX, and X-ray diffraction. The antibacterial efficacy of the Ag-NPs was also determined against some pathogenic Gram-negative and Gram-positive bacteria using the microdilution method.</p><p><strong>Results: </strong>Glucose and galactose are the major monomers among the extracted carbohydrates. Various types of spectral analysis confirmed the formation of Ag-NPs. The green synthesized Ag-NPs have the average diameter of about 28 nm. Furthermore, the green synthesized Ag-NPs exhibited strong antibacterial activity against some pathogenic Gram-positive (<em>L. cytomonogenes, Bacillus Subtilis, </em>and <em>Staphylococcus aureus</em>) and Gram-negative (<em>Salmonella typhimurium </em>and <em>Escherichia coli</em>) bacteria.</p><p><strong>Conclusion: </strong>The green synthesis of Ag-NPs using plant polysaccharide was an environment-friendly and cost-effective method as compared to the conventional physical and chemical synthesis techniques.</p> ER -