TY - JOUR AU - ANDAYANI, REGINA AU - ARMIN, FITHRIANI AU - MARDHIYAH, AINUL PY - 2020/08/07 Y2 - 2024/03/29 TI - DETERMINATION OF THE TOTAL PHENOLICS AND ANTIOXIDANT ACTIVITY IN THE RIND EXTRACTS OF GARCINIA MANGOSTANA L., GARCINIA COWA ROXB., AND GARCINIA ATROVIRIDIS GRIFF. EX T. ANDERS. JF - Asian Journal of Pharmaceutical and Clinical Research JA - Asian J Pharm Clin Res VL - 13 IS - 8 SE - Original Article(s) DO - 10.22159/ajpcr.2020.v13i8.36525 UR - https://journals.innovareacademics.in/index.php/ajpcr/article/view/36525 SP - 149-152 AB - <p><strong>Objectives: </strong><em>Garcinia atroviridis </em>Griff. ex T. Anders., <em>Garcinia mangostana </em>L., and <em>Garcinia cowa </em>Roxb. are plants of the genus Garcinia that has been widely used by the community as a food flavoring, spices, and also as a herbal medicinal ingredient. This research aimed to evaluate the total phenolics and antioxidant activity from three species of Garcinia (<em>G. atroviridis </em>Griff. ex T. Anders., <em>G. mangostana </em>L.<em>, </em>and <em>G. cowa </em>Roxb.)</p><p><strong>Methods: </strong>The total phenolic content (TPC) of the extracts was estimated as Gallic Acid Equivalent by the Folin-Ciocalteu method. Antioxidant activity was assessed using Ferric Reducing Antioxidant Power assay.</p><p><strong>Results: </strong>The TPC of <em>G. mangostana </em>L. rind extract is higher (31.83±3.70%), than <em>G. cowa </em>Roxb.(4.35±0.17%) and <em>G. atroviridis </em>Griff. ex T. Anders. (2.47±0.42%). Based on the antioxidant activity, <em>G. mangostana </em>L. rind has a higher total antioxidant activity (24.68 μmol Fe(II)/g) than <em>G. cowa </em>Roxb. (18.88±0.12 μM Fe (II)/g and <em>G. atroviridis </em>Griff. ex T. Anders.(17.61±0.05 μM Fe(II)/g).</p><p><strong>Conclusion: </strong>The results showed that <em>G. mangostana </em>L rind extract contains a higher level of TPC and antioxidant activity among the other rinds. The results obtained indicate that the three samples have the potential to be a source of natural antioxidants. Further studies must be carried out to isolate compounds that have antioxidant activity.</p> ER -