TY - JOUR AU - AL-HULU, SAMER M. PY - 2020/07/07 Y2 - 2024/03/29 TI - ANTIBACTERIAL ACTIVITY FOR BIOSURFACTANT PRODUCED BY STREPTOMYCES SPP. ISOLATED FROM SOIL SAMPLES JF - Asian Journal of Pharmaceutical and Clinical Research JA - Asian J Pharm Clin Res VL - 13 IS - 7 SE - Original Article(s) DO - 10.22159/ajpcr.2020.v13i7.37472 UR - https://journals.innovareacademics.in/index.php/ajpcr/article/view/37472 SP - 109-110 AB - <p><strong>Objective: </strong>The goal of the present study on isolation <em>Streptomyces </em>from soil samples with biosurfactant activity and antibacterial activity analysis.</p><p><strong>Methods: </strong>(25) The soil samples were taken form Hilla city. (10) It is <em>Streptomyces </em>spp. They were identified. (4) <em>Streptomyces </em>spp. having the ability to hemolysis on blood agar that has the capacity to generate biosurfactants. <em>Streptomyces </em>spp. 8 displayed a high degree of activity by having a blood agar inhibition zone (25 mm).</p><p><strong>Results: </strong>Antibacterial activity was evaluated for <em>Streptomyces </em>spp. 8 (<em>Staphylococcus aureus</em>, <em>Escherichia Coli, </em>and <em>Pseudomonas aeruginosa</em>). <em>Streptomyces </em>spp. 8 has greatest inhibition zone against <em>S. aureus </em>equal to 14 mm compared 12 mm against <em>E. coli </em>and 8 mm for <em>P. aeruginosa</em>. This <em>Streptomyces </em>spp. 8 characteristic was tested, it showed Gram positive with aerial mycelium gray in color on yeast malt extract agar. Negative for melanin produced on tyrosine broth medium, negative for H2S output, and pigment development, it has for the use of mannitol sucrose, glucose, and fructose as carbon source and negative for xylose.</p><p><strong>Conclusion: </strong>Isolated <em>Streptomyces </em>spp. having the potential to generate biosurfactants with antibacterial activity.</p> ER -